Differential diagnosis of Covid-19 and NOVICHOK or other chemical agent poisoning - Google Search (Apr 15, 2020 12:04)

An illustration of the coronavirus entering a cartoon mans airways and his brain


Differential diagnosis of Covid-19 and NOVICHOK or other chemical agent poisoning



https://tweetsandnews.blogspot.com/2020/04/differential-diagnosis-of-covid-19-and.html
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differential diagnosis of covid-19 and NOVICHOK or other chemical agent poisoning - Google Search (Apr 15, 2020 12:04)
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Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China | Infectious Diseases | JAMA Neurology | JAMA Network (Apr 15, 2020 11:49)
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differential diagnosis of covid-19 - Google Search (Apr 15, 2020 11:44)
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Novichok agents: a historical, current, and toxicological perspective (Apr 15, 2020 11:39)
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mikenov on Twitter: How does Novichok kill and what does the nerve agent do to the human body? thesun.co.uk/news/6729712/h… (Apr 15, 2020 11:34)
How does Novichok kill and what does the nerve agent do to the human body? thesun.co.uk...

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mikenov on Twitter: All Your Coronavirus Questions, Answered ti.me/3a3GFG5?utm_so… (Apr 15, 2020 11:19)
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mikenov on Twitter: Dermatological symptoms may be the latest new coronavirus symptom jpost.com/International/… (Apr 15, 2020 11:08)
Dermatological symptoms may be the latest new coronavirus symptom jpost.com/Internation...

mikenov on Twitter: What We Know About The Silent Spreaders Of COVID-19 npr.org/sections/goats… (Apr 15, 2020 11:06)
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mikenov on Twitter: Did I Have the Coronavirus? nytimes.com/2020/04/13/opi… (Apr 15, 2020 10:58)
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mikenov on Twitter: Tweets And News - From Michael Novakhov: » Mayor de Blasio touts $25 million in emergency f... tweetsandnews.blogspot.com/2020/04/mayor-… (Apr 15, 2020 10:39)
Tweets And News - From Michael Novakhov: » Mayor de Blasio touts $25 million in emergen...

More than 8,200 coronavirus cases on Staten Island; fatality number continues to rise (Apr 15, 2020 09:53)
Michael_Novakhov shared this story . STATEN ISLAND – The number of coronavirus (COVID-1...

mikenov on Twitter: New Johns Hopkins map breaks down COVID-19 data by county, shows demographic information wmar2news.com/news/coronavir… (Apr 15, 2020 09:49)
New Johns Hopkins map breaks down COVID-19 data by county, shows demographic informatio...

mikenov on Twitter: COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features | Radiology pubs.rsna.org/doi/10.1148/ra… (Apr 15, 2020 09:27)
COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features |...

What explains the non-respiratory symptoms seen in some COVID-19 patients? Wed, 15 Apr 2020 08:34: Saved and Shared Stories (Apr 15, 2020 09:05)
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mikenov on Twitter: Let them mind their own FUCKING bidniz and put up the money themselves, if they want to. twitter.com/thehill/status… (Apr 15, 2020 08:41)
Let them mind their own FUCKING bidniz and put up the money themselves, if they want to...

mikenov on Twitter: RT @NBCNews: Passwords and email addresses for thousands of Zoom accounts are for sale on the dark web. nbcnews.to/2REfICq (Apr 15, 2020 08:38)
Passwords and email addresses for thousands of Zoom accounts are for sale on the dark w...

mikenov on Twitter: RT @mod_russia: Экипажи фронтовых бомбардировщиков Су-24М авиаполка Южного военного округа, дислоцированного в Волгоградской области, прист… (Apr 15, 2020 08:38)
Экипажи фронтовых бомбардировщиков Су-24М авиаполка Южного военного округа, дислоцирова...

mikenov on Twitter: RT @BreitbartNews: Wow. trib.al/D6yWwpz (Apr 15, 2020 08:37)
Wow. trib.al/D6yWwpz Posted by BreitbartNews on Wednesday, April 15th, 2020 11:42am Ret...

mikenov on Twitter: RT @tribelaw: Grim but sadly true (Apr 15, 2020 08:37)
Grim but sadly true

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“Never in my life have I had to ask a patient to get off the telephone because it was t...

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mikenov on Twitter: RT @USNavy: Social distancing doesn't mean you are alone! #ReachOutWednesday Pick up the phone or grab a computer and call a Shipmate, fam… (Apr 15, 2020 08:35)
Social distancing doesn't mean you are alone! #ReachOutWednesday Pick up the phone or g...

mikenov on Twitter: RT @tribelaw: Apart from inexcusably slowing the checks, this display of ego is a reminder to all of us that the one and only thing Donald… (Apr 15, 2020 08:35)
Apart from inexcusably slowing the checks, this display of ego is a reminder to all of ...

mikenov on Twitter: RT @Pontifex: They are called children of God who have learned the art of peace and exercise it, knowing that there is no reconciliation wi… (Apr 15, 2020 08:34)
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mikenov on Twitter: COVID-19 affects more than the lungs cen.acs.org/content/cen/ar… via @cenmag (Apr 15, 2020 08:34)
COVID-19 affects more than the lungs cen.acs.org/content/cen/ar… via @cenmag Posted by ...

What explains the non-respiratory symptoms seen in some COVID-19 patients? (Apr 15, 2020 08:34)
Michael_Novakhov shared this story . Credit: C&EN/Shutterstock While COVID-19 is pr...

New York City hospitals cancel temporary workers as coronavirus cases stabilize (Apr 15, 2020 08:31)
Michael_Novakhov shared this story from Yahoo News - Latest News & Headlines. 'Acce...

mikenov on Twitter: New York City hospitals cancel temporary workers as coronavirus cases stabilize news.yahoo.com/nyc-hospitals-… (Apr 15, 2020 08:27)
New York City hospitals cancel temporary workers as coronavirus cases stabilize news.ya...

mikenov on Twitter: saliva-based coronavirus test - Google Search google.com/search?q=saliv… (Apr 15, 2020 08:22)
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mikenov on Twitter: Intelligence officials weigh possibility coronavirus escaped from a Chinese lab news.yahoo.com/intelligence-o… (Apr 15, 2020 08:17)
Intelligence officials weigh possibility coronavirus escaped from a Chinese lab news.ya...

Fauci once dismissed concerns about 'silent carriers' of coronavirus. Not anymore. (Apr 15, 2020 08:07)
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mikenov on Twitter: RT @YahooNews: Dr. Anthony Fauci once dismissed concerns about 'silent carriers' of coronavirus, but not anymore. Here's what changed. (Apr 15, 2020 07:31)
Dr. Anthony Fauci once dismissed concerns about 'silent carriers' of coronavirus, but n...

mikenov on Twitter: RT @MiddleEastMnt: Saudi Arabia carried out 800 executions under King Salman middleeastmonitor.com/20200415-saudi… pic.twitter.com/FuQ3Xsw5Ps (Apr 15, 2020 07:30)
Saudi Arabia carried out 800 executions under King Salman middleeastmonitor.com/2020041...

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mikenov on Twitter: RT @CNNPolitics: Fact check: President Trump denies saying another thing he said and makes more false claims at coronavirus briefing https:… (Apr 15, 2020 07:29)
Fact check: President Trump denies saying another thing he said and makes more false cl...

mikenov on Twitter: RT @tribelaw: As we watch the disgraceful daily display put on by this inept, narcissistic president, I find myself thinking: America must… (Apr 15, 2020 07:29)
As we watch the disgraceful daily display put on by this inept, narcissistic president,...

mikenov on Twitter: RT @washingtonpost: Live updates: As U.S. death toll soars, Trump accuses WHO of coronavirus cover-up and suspends funding https://t.co/KTQ… (Apr 15, 2020 07:28)
Live updates: As U.S. death toll soars, Trump accuses WHO of coronavirus cover-up and s...

mikenov on Twitter: RT @AmbJohnBolton: Withholding US funding from @WHO is the correct response to its coronavirus failures and Chinese influence. It should b… (Apr 15, 2020 07:28)
Withholding US funding from @WHO is the correct response to its coronavirus failures an...

Officials Told ‘Bodies Being Piled Up In Nursing Homes’ As Desperate Families Face Silence – CBS New York (Apr 15, 2020 07:19)
Michael_Novakhov shared this story from CBS New York. NEW YORK (CBSNewYork) – Some say ...

mikenov on Twitter: Coronavirus Deaths: Officials Told 'Bodies Being Piled Up In Nursing Homes' As Desperate Families Face Silence cbsloc.al/2XzVrlq#.Xpbte… (Apr 15, 2020 07:18)
Coronavirus Deaths: Officials Told 'Bodies Being Piled Up In Nursing Homes' As Desperat...

mikenov on Twitter: RT @washingtonpost: Islamic State cell plotted attacks on U.S. bases in Germany, prosecutors say wapo.st/3betNyg (Apr 15, 2020 07:07)
Islamic State cell plotted attacks on U.S. bases in Germany, prosecutors say wapo.st/3b...

mikenov on Twitter: #MayorDeBlasio #GovernorCuomo #NYC #NY #FIRE #STUPID #BRAINLESS #HHC #BUREAUCRATS FOR #INABILITY TO #ORGANIZE #PROPER #CARE & #SAFEGUARDS FOR #STAFF! IT IS THEIR #FAULT! #FIRETHEM #NOW! Up to 20% of #Coronavirus cases are the #he (Apr 15, 2020 07:02)
#MayorDeBlasio #GovernorCuomo #NYC #NY #FIRE #STUPID #BRAINLESS #HHC #BUREAUCRATS FOR #...

mikenov on Twitter: Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM coronavirusalerts.org/?p=75 (Apr 15, 2020 06:47)
Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15t...

mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro (Apr 15, 2020 06:46)
Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/0...

mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #STUPID! #BRAINLESS! #HHC: #Staff #sickouts #skyrocket at #NYC #hospitals amid #coronavirusoutbreak Wednes (Apr 15, 2020 06:44)
#CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #Coronav...

Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM (Apr 15, 2020 06:35)
Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov. https:...

Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak (Apr 15, 2020 06:16)
Michael_Novakhov shared this story from Carl Campanile – New York Post. Skip to main co...

mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro (Apr 15, 2020 06:16)
Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/0...

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mikenov on Twitter: Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false', via @nzherald nzherald.co.nz/nz/news/articl… (Apr 14, 2020 21:01)
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Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false' (Apr 14, 2020 21:00)
Michael_Novakhov shared this story from New Zealand Herald - Top Stories. When a new fl...

Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously ... (Apr 14, 2020 20:57)
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mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #Putin #UN #OperationCoronaVirus #Update: "#HealthCareWorkers are 10%-20% of #USCoronavirusCases" tweetsa (Apr 14, 2020 20:51)
#CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #Coronav...

mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #Putin #UN #CoronavirusPandemicInvestigations #CoronavirusGermany #OperationCoronaVirus #Update: "#HealthCa (Apr 14, 2020 20:48)
#CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #Coronav...

7:57 PM 4/14/2020 - Operation CoronaVirus Update: "Health care workers are 10%-20% of US coronavirus cases" (Apr 14, 2020 20:43)
Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov. Health...

mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/quTyP7SxoBaGsM… (Apr 14, 2020 17:50)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/spjm63uykpATWu… (Apr 14, 2020 17:50)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/2BiB3dqiwPXUzb… (Apr 14, 2020 17:49)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/jnCd87icTgTLJn… (Apr 14, 2020 17:49)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/Hb4bxJDvMWp8Ts… (Apr 14, 2020 17:48)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/tfg1Akn6kNFiRc… (Apr 14, 2020 17:48)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/c1fRPq5zW4K98y… (Apr 14, 2020 17:48)
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mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search google.com/search?q=Coron… (Apr 14, 2020 17:46)
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differential diagnosis of covid-19 and NOVICHOK or other chemical agent poisoning - Google Search
Wed, 15 Apr 2020 12:04:32 -0400
Michael_Novakhov shared this story .

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Information on vesicants -- potential agents for chemical terrorism. ... Toxic Syndrome Description: Nerve Agent and Organophosphate Pesticide Poisoning Includes comprehensive signs & symptoms & differential diagnosis. ... This educational case study document is one in a series of self-instructional publications designed ...

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Chemical warfare agent NOVICHOK - mini-review of available ...


<a href="http://www.sciencedirect.com" rel="nofollow">www.sciencedirect.com</a> › science › article › pii
by E Nepovimova - ‎2018 - ‎Cited by 19 - ‎Related articles
Within various programs on both sides, a wide scale of different agents have been ... to V-agents that will be undetectable using NATO standard chemical detection ... this incident as poisoning with a nerve agent from the Novichok group. ... Overstimulation of muscarinic cholinergic receptors causes pupils constriction, ...

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What is Novichok? Nerve agent used to poison ex-Russian ...


<a href="http://nationalpost.com" rel="nofollow">nationalpost.com</a> › World › News
Mar 13, 2018 - Novichok is a group of agents known as fourth generation chemical weapons that were developed by the Russians in the 1970s and 1980s.
Combating the coronavirus pandemic: Bosch develops rapid test for Covid-19
Wed, 15 Apr 2020 12:01:00 -0400
Michael_Novakhov shared this story from Motors Actu.


The coronavirus SARS-CoV-2 is posing major challenges for healthcare systems and medical institutions worldwide. An ability to rapidly diagnose the virus is of invaluable help in curbing its exponential spread in many countries. Bosch’s new, fully automated rapid test for COVID-19 can help medical facilities such as doctors’ offices, hospitals, laboratories, and health centers make fast diagnoses. The rapid molecular diagnostic test runs on the Vivalytic analysis device from Bosch Healthcare Solutions. “We want the Bosch rapid COVID-19 test to play a part in containing the coronavirus pandemic as quickly as possible. It will speed up the identification and isolation of infected patients,” says Dr. Volkmar Denner, chairman of the board of management of Robert Bosch GmbH.
“Bosch’s rapid COVID-19 test will help contain the spread of the pandemic and break the chain of transmission more quickly.” Bosch CEO Dr. Volkmar Denner
Faster certainty, slower spread
Developed in just six weeks, the rapid test can detect a SARS-CoV-2 coronavirus infection in patients in under two and a half hours – measured from the time the sample is taken to the time the result arrives. Another advantage of the rapid test is that it can be performed directly at the point of care. This eliminates the need to transport samples, which takes up valuable time. It also means patients quickly gain certainty about their state of health, while allowing infected individuals to be identified and isolated immediately. With the tests currently in use, patients must usually wait one to two days for a result. “Time is of the essence in the fight against coronavirus. Reliable, rapid diagnosis directly on site with no back and forth – that is the great advantage of our solution, which we see as another example of technology that is ‘Invented for life,” Denner says.
Differential diagnosis: diagnosing ten respiratory pathogens simultaneously
Bosch’s rapid test is one of the world’s first fully automated molecular diagnostic tests that can be used directly by all medical institutions. What’s more, it allows a single sample to be tested not just for COVID-19 but also for nine other respiratory diseases, including influenza A and B, simultaneously. “The special feature of the Bosch test is that it offers differential diagnosis, which saves doctors the additional time needed for further tests. It also provides them with a reliable diagnosis quickly so they can then begin suitable treatment faster,” says Marc Meier, president of Bosch Healthcare Solutions GmbH. The newly developed test will be available in Germany starting in April, with other markets in Europe and elsewhere to follow.
Bosch’s rapid COVID-19 test is the result of collaboration between the company’s Bosch Healthcare Solutions subsidiary and the Northern Irish medical technology company Randox Laboratories Ltd. “Together with our partner Randox, we have succeeded in developing this innovative rapid test within a very short time frame, and we are now in a position to offer it to the market. The Bosch Vivalytic analysis device evaluates the test safely and reliably directly in the hospital, in the lab, or in the doctor’s office, guaranteeing the best possible protection for patients and medical staff,” Meier says. The company is currently examining how it can help doctors and nursing staff in medical facilities such as the Robert Bosch Hospital get tested promptly so they can be fit to work for as long as possible – with no risk of infecting others.
Easy application at the point of care
In various laboratory tests with SARS-CoV-2, the Bosch test delivered results with an accuracy of over 95 percent. The rapid test meets the quality standards of the World Health Organization (WHO). A sample is taken from the patient’s nose or throat using a swab. Then the cartridge, which already contains all the reagents required for the test, is inserted into the Vivalytic device for analysis. During the analysis, medical staff can devote themselves to other tasks, for example treating patients. The Vivalytic analyzer is designed to be so user-friendly that even medical personnel who have not been specially trained on it can reliably perform the test. A Bosch Vivalytic analyzer can perform up to ten tests in the space of 24 hours. This means it takes just 100 devices to evaluate up to 1,000 tests per day. Given the dynamic spread of the coronavirus SARS-CoV-2, laboratories are already working beyond capacity. The Bosch Vivalytic will thus help to increase available testing capacities.
First Report of COVID-19 Neurologic Symptoms in China
Wed, 15 Apr 2020 11:57:12 -0400
Michael_Novakhov shared this story .


An illustration of the coronavirus entering a cartoon mans airways and his brain
More than a third of 214 confirmed COVID-19 cases in China had neurologic symptoms, researchers said.
Acute cerebrovascular events, impaired consciousness, and muscle injury were seen in 36.4% of patients and were more common (45.5%) in patients with severe infection who required mechanical ventilation, reported Bo Hu, MD, PhD, of Union Hospital and Huazhong University of Science and Technology in Wuhan, and colleagues.
Neurologic symptoms included central nervous system (CNS) manifestations such as dizziness, headache, impaired consciousness, acute cerebrovascular disease, ataxia, or seizure; peripheral nervous system manifestations such as taste and smell impairment, vision impairment, or nerve pain; and skeletal muscular injury manifestations.
"For those with severe COVID-19, rapid clinical deterioration or worsening could be associated with a neurologic event such as stroke, which would contribute to its high mortality rate," the team wrote in JAMA Neurology. "During the epidemic period of COVID-19, when seeing patients with these neurologic manifestations, clinicians should consider SARS-CoV-2 [the virus that causes COVID-19] infection as a differential diagnosis to avoid delayed diagnosis or misdiagnosis and prevention of transmission."
COVID-19 and severe acute respiratory syndrome (SARS), which first appeared in China in late 2002, are similar in many ways clinically, noted S. Andrew Josephson, MD, of the University of California San Francisco, and colleagues, in an accompanying editorial.
"Although the SARS epidemic was limited to about 8,000 patients worldwide, there were some limited reports of neurologic complications of SARS that appeared in patients 2 to 3 weeks into the course of the illness, mainly consisting of either an axonal peripheral neuropathy or a myopathy with elevated creatinine kinase," the editorialists wrote. Pathology showed that patients with SARS had widespread vasculitis in many organs, including striated muscle, "suggesting that the clinical features in these neuromuscular patients might be more than just nonspecific complications of severe illness," Josephson and co-authors continued.
For the study, Hu and colleagues reported data on 214 consecutive laboratory-confirmed COVID-19 patients between Jan. 16 and Feb. 19, 2020. Patients had an average age of about 53 ± 15.5 years, and 41% were men.
About 41% of patients had severe infection and required mechanical ventilation. Those with severe infection were older, had more underlying disorders, especially hypertension, and showed fewer typical symptoms of COVID-19 such as fever and cough compared with people with non-severe infection.
Patients with more severe infection had a higher occurrence of acute cerebrovascular diseases (5.7% vs 0.8%), impaired consciousness (14.8% vs 2.4%), and skeletal muscle injury (19.3% vs 4.8%) than people with non-severe infection.
Of the 214 patients, 12 (5.6%) had taste impairment, 11 (5.1%) had smell impairment, and three (1.4%) had vision impairment. Five patients reported nerve pain.
Most neurologic manifestations occurred early in the illness; the median time to hospital admission was 1 to 2 days. Some patients without typical COVID-19 symptoms came to the hospital with only neurologic manifestations as their presenting symptoms, the researchers noted.
Angiotensin-converting enzyme 2 (ACE2) has been identified as the functional receptor for SARS-CoV-2, and "the expression and distribution of ACE2 remind us that the SARS-CoV-2 may cause some neurologic manifestations through direct or indirect mechanisms," the investigators wrote. "Autopsy results of patients with COVID-19 showed that the brain tissue was hyperemic and edematous and some neurons degenerated."
Neurologic injury has been confirmed not only in SARS, but also in Middle East respiratory syndrome (MERS), Hu and co-authors noted. CNS symptoms were the main form of neurologic injury in COVID-19 in this study, and the pathologic mechanism may be from the CNS invasion of SARS-CoV-2, similar to SARS and MERS viruses, the team speculated.
"As with other respiratory viruses, SARS-COV-2 may enter the CNS through the hematogenous or retrograde neuronal route," the researchers suggested. "The latter can be supported by the fact that some patients in this study had smell impairment."
People with severe infection had higher D-dimer levels than patients with non-severe infection, the investigators observed. Patients with muscle symptoms had higher creatine kinase and lactate dehydrogenase levels than those without muscle symptoms, and creatine kinase and lactate dehydrogenase levels in patients with severe infection were much higher than those of patients with non-severe infection.
Whether axonal neuropathy is part of COVID-19 is unknown from this study; the researchers could not obtain nerve conduction studies or lumbar punctures. "Given the likely shared vasculitic pathology of SARS and COVID-19, it seems probable that further studies will reveal neuropathy as another rare finding in COVID-19," Josephson and co-authors pointed out.
The more dramatic neurologic symptoms -- stroke, ataxia, seizure, and depressed level of consciousness -- were more common in severely affected patients, the editorialists observed. But these associations may reflect that people with more severe complications are more likely to have medical comorbidities, especially vascular risk factors like hypertension: "The occurrence of cerebrovascular events in critically ill patients with underlying high blood pressure and cardiovascular disease is therefore potentially unrelated to a direct effect of the infection itself or an inappropriate host response," Josephson and co-authors wrote.
They added: "It is clear that this small series does not reflect the entire spectrum of neurologic disease in COVID-19 disease, and much is left to be learned with thorough neurologic testing in large data sets of patients with COVID-19."
Disclosures
The research was supported by the National Key Research and Development Program of China, the National Natural Science Foundation of China, and Major Refractory Diseases Pilot Project of Clinical Collaboration with Chinese and Western Medicine.
The researchers reported no conflicts of interest.
The editorialists reported relationships with the National Institute of Mental Health, the Weill Institute for Neuroscience, the Brain Research Foundation, the George and Judy Marcus Fund for Innovation, Viela Bio, Mylan, Bionure, Neurona, Pipeline Therapeutics, and Inception Sciences.
Additional Source
Source Reference:
Diagnostic Testing for SARS–CoV-2 | Annals of Internal Medicine | American College of Physicians
Wed, 15 Apr 2020 11:56:18 -0400
Michael_Novakhov shared this story from Annals of Internal Medicine Current Issue.

Conclusion


The COVID-19 pandemic has dramatically highlighted the essential role of diagnostics in the control of communicable diseases. Intensive diagnostics deployment probably contributed to the success of a few countries in controlling transmission. Urgent clinical and public health needs now drive an unprecedented global effort to increase SARS–CoV-2 testing capacity. Finally, the blinding speed with which COVID-19 has spread illustrates the need for preparedness and long-term investments in diagnostic testing.
Neurologic effects seen in a third of hospitalized COVID-19 patients
Wed, 15 Apr 2020 11:52:45 -0400
Michael_Novakhov shared this story .

Neurologic effects seen in a third of hospitalized COVID-19 patients

Neurologic manifestations are common among hospitalized patients with COVID-19, according to a study published online April 10 in JAMA Neurology.
Ling Mao, from Tongji Medical College at the Huazhong University of Science and Technology in Wuhan, China, and colleagues retrospectively reviewed data from 214 consecutive hospitalized patients with a laboratory-confirmed diagnosis of severe acute respiratory syndrome coronavirus 2 infection (SARS-CoV-2), treated from Jan. 16, 2020, to Feb. 19, 2020, at three designated special care centers.
The researchers note that 126 patients (58.9 percent) had nonsevere infection and 88 patients (41.1 percent) had severe infection, according to their respiratory status. Just over one-third of patients (36.4 percent) had neurologic manifestations overall versus 45.5 percent among patients with severe infection. Neurologic manifestations, such as acute cerebrovascular diseases (5.7 versus 0.8 percent), impaired consciousness (14.8 versus 2.4 percent), and skeletal muscle injury (19.3 versus 4.8 percent), were more common among patients with severe infection versus nonsevere infection.
"During the epidemic period of COVID-19, when seeing patients with these neurologic manifestations, clinicians should consider SARS-CoV-2 infection as a differential diagnosis to avoid delayed diagnosis or misdiagnosis and prevention of transmission," the authors write.
Coronavirus harms the brain and nerves of HALF of severely ill patients and a third of all cases
Wed, 15 Apr 2020 11:51:19 -0400
Michael_Novakhov shared this story from Science & tech | Mail Online.

Coronavirus harms the brain and nervous system of half of severely ill patients, a study on patients with COVID-19 in the Chinese city of Wuhan has found.
Such impacts — which appear in a third of patients overall — lead to symptoms including headaches, stumbling, slurred speech, nerve pain and seizures.
The study — the first to characterise the brain problems associated with coronavirus infection — suggest that these symptoms could indicate patients at a higher risk.
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Coronavirus harms the brain and nervous system of HALF of severely ill patients, a study on patients with COVID-19 in the Chinese city of Wuhan has found (stock image)
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Coronavirus harms the brain and nervous system of HALF of severely ill patients, a study on patients with COVID-19 in the Chinese city of Wuhan has found (stock image)
In the study, neurologist Bo Hu of the Huazhong University of Science and Technology and colleagues analysed 214 patients with COVID-19 from Wuhan, China, the city where the outbreak emerged, between mid-January and mid-February.
The patients were all treated in one of three dedicated special care centres in the university's Union Hospital.
The experts sorted neurological symptoms into one of three categories, the first of which was central nervous system manifestations — including dizziness, headache, impaired consciousness, acute cerebrovascular disease, ataxia and seizure.
The other categories were peripheral nervous system manifestations (taste impairment, smell impairment, vision impairment and nerve pain) and skeletal muscular injury manifestations.

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'Overall, 78 patients (36.4 per cent) had neurologic manifestations,' the researchers wrote in their paper.
'Compared with patients with non-severe infection, patients with severe infection were older, had more underlying disorders, especially hypertension, and showed fewer typical symptoms of COVID-19, such as fever and cough,' they added.
'Patients with more severe infection had neurologic manifestations, such as acute cerebrovascular diseases (5 vs 1), impaired consciousness (13 vs 3) and skeletal muscle injury (17 vs 6).'
The study — the first to characterise the brain problems associated with coronavirus infection — suggest that neurological symptoms could indicate patients who are at a higher risk. Pictured, a computed tomography (CT) image of the brain of a patient with COVID-19
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The study — the first to characterise the brain problems associated with coronavirus infection — suggest that neurological symptoms could indicate patients who are at a higher risk. Pictured, a computed tomography (CT) image of the brain of a patient with COVID-19
'During the epidemic period of COVID-19, when seeing patients with neurologic manifestations, clinicians should suspect severe acute respiratory syndrome coronavirus 2 infection as a differential diagnosis,' the researchers said.
This, they added, will avoid delayed diagnosis or misdiagnosis and losing the chance to treat [the patients] and prevent further transmission.'
'The observations of neurological complications in a subset of COVID-19 positive patients is worthy of note but should not distract from a focus on the main pathology of respiratory distress,' commented virologist Ian Jones of the University of Reading.
'Almost half of the patients described here had underlying health issues and there is no direct data given on the presence of virus at neurological sites.'
'Viraemia, the presence of virus in the bloodstream, from where it can access neuronal tissue, was described for SARS but not in all patients and then only transiently. It happens, but is generally not what coronaviruses do.'
'At the moment neurological complications might best be considered a consequence of COVID-19 disease severity rather than a distinct new concern.'
The full findings of the study were published in the journal JAMA Neurology.

WHAT ARE THE MOST COMMON CORONAVIRUS SYMPTOMS? 

The virus, called COVID-19, is transmitted from person to person via droplets when an infected person breathes out, coughs or sneezes.
It can also spread via contaminated surfaces such as door handles or railings.
Coronavirus infections have a wide range of symptoms, including fever, coughing, shortness of breath and breathing difficulties.
Mild cases can cause cold-like symptoms including a sore throat, headache, fever, cough or trouble breathing.
Severe cases can cause pneumonia, severe acute respiratory illness, kidney failure and death.
Symptoms may appear 2-14 days after exposure.
Dominic Raab answers questions from reporters on coronavirus
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Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China | Infectious Diseases | JAMA Neurology | JAMA Network
Wed, 15 Apr 2020 11:49:37 -0400
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Original Investigation
April 10, 2020

Neurologic Manifestations of Hospitalized Patients With Coronavirus Disease 2019 in Wuhan, China

Author Affiliations 
  • 1Department of Neurology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • 2Department of Hematology, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • 3Department of Epidemiology and Biostatistics, Key Laboratory for Environment and Health, School of Public Health, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China
  • 4Neurovascular Division, Department of Neurology, Barrow Neurological Institute, Saint Joseph’s Hospital and Medical Center, Phoenix, Arizona
JAMA Neurol. Published online April 10, 2020. doi:10.1001/jamaneurol.2020.1127
Key PointsQuestion  What are neurologic manifestations of patients with coronavirus disease 2019?
Findings  In a case series of 214 patients with coronavirus disease 2019, neurologic symptoms were seen in 36.4% of patients and were more common in patients with severe infection (45.5%) according to their respiratory status, which included acute cerebrovascular events, impaired consciousness, and muscle injury.
Meaning  Neurologic symptoms manifest in a notable proportion of patients with coronavirus disease 2019.

Abstract
Importance  The outbreak of coronavirus disease 2019 (COVID-19) in Wuhan, China, is serious and has the potential to become an epidemic worldwide. Several studies have described typical clinical manifestations including fever, cough, diarrhea, and fatigue. However, to our knowledge, it has not been reported that patients with COVID-19 had any neurologic manifestations.
Objective  To study the neurologic manifestations of patients with COVID-19.
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Wed, 15 Apr 2020 11:44:53 -0400
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Novichok agents: a historical, current, and toxicological perspective
Wed, 15 Apr 2020 11:39:47 -0400
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Toxicol Commun. Author manuscript; available in PMC 2019 Jun 29.
Published in final edited form as:
PMCID: PMC6039123
NIHMSID: NIHMS978806
PMID: 30003185

Novichok agents: a historical, current, and toxicological perspective

Abstract

The Novichok, or “newcomer” class of nerve agents are lesser characterized, weaponized organophosphate agents. The use of known Novichok agents in warfare is banned under the Chemical Weapons Convention of 1997. Novichok agents are considered more potent than VX gas and can be applied in unitary and binary forms. Like other nerve agents, Novichok agents irreversibly bind acetylcholinesterase and produce a cholinergic toxidrome. Uniquely, these agents are thought to also target neurons in the peripheral nervous system. Delayed treatment or massive exposure may therefore cause a debilitating neuropathy. The recent 2018 assassination attempt of Russian dissident Sergei Skripal and his daughter Yulia in the United Kingdom highlights the importance of recognizing the potential lethal effects of these nerve agents. Treatment of Novichok agent poisoning is similar to management of other nerve agents. Given increasing worldwide incidents attributed to chemical weapons such as Novichok agents, clinicians should know how to rapidly recognize symptoms of acute poisoning and administer life-saving antidotal therapy, when indicated.
Keywords: Novichok, nerve agents, organophosphates, chemical weapons
“Circles appeared before my eyes: red and orange. A ringing in my ears, I caught my breath. And a sense of fear: like something was about to happen. I sat down on a chair and told the guys: it’s got me”
––Andrei Zheleznyakov, Russian military researcher after he was exposed to Novichok-5 from a malfunctioning fume hood (1987) [1].
On 4 March 2018, Sergei Skripal, a former Russian military intelligence officer, and his daughter, Yulia Skripal collapsed on a park bench in Salisbury, United Kingdom after eating dinner at a local restaurant [2]. The Skripals were rapidly transported to the hospital where they received treatment for a presumed nerve agent exposure. A responding police officer also developed symptoms of nerve agent poisoning and was admitted to the hospital. A few days later, the media reported that biological sampling of the Skripals confirmed the presence of Novichok, a highly potent nerve agent developed as part of the Russian classified nerve agent program, FOLIANT [3]. One month later, scientists from the Organization for the Prohibition of Chemical Weapons (OPCW) confirmed the presence of Novichok in biological sampling from the Skripals as well as from the site of suspected exposure. At the time of this writing, Yulia has fully recovered and was discharged from the hospital, and Sergei remains hospitalized but is expected to recover.
The attempted assassination of the Skripals mirrors the recent assassination of Kim Jong-Nam, brother of North Korean dictator Kim Jong-Un, using ethyl N-2-diisopropylaminoethyl methylphosphonothiolate (VX) [4]. The use of Novichok, a rare and classified organophosphate, is especially concerning. Here, we review the known toxicity and effects of the Novichok class of organophosphate agents and describe the role of toxicologists in advocating for the ban of these chemical weapons as well as global compliance with the 1997 Chemical Weapons Convention that prohibits the large-scale use, development, production, stockpiling, and transfer of chemical weapons and their precursors [5].
Most of what we understand of Novichok agents comes from testimony and memoirs of Dr. Vil S. Mirzayanov, the Chief of the Department of Counteraction against Foreign Technical Intelligence at the Russian State Union Scientific Research Institute for Organic Chemistry and Technology (GosNIIOKhT) [6]. Dr. Mirzayanov authored a 1994 report with the Stimson Center describing the state of chemical weapon disarmament in Russia [7]. He detailed the initiation of a secret Soviet chemical weapons initiative to develop “newcomer” (i.e. Novichok in Russian) agents. The first three of these, Substance-33, A-230, and A-232, were produced at a GosNIIOKhT facility Russia using an organophosphate structural backbone (Figure 1) [7]. These three newcomer agents were synthesized much like VX, tabun, soman, and sarin, as unitary agents, meaning that the chemical structure is altered during production so that maximum potency occurs rapidly at the outset. Importantly, only binary agents (two inert substances that are combined prior to delivery to create the active nerve agent) that were effectively weaponized and tested were given the designator Novichok, while unitary agents and other organophosphates maintain their original designators. For the purposes of this review, we will refer to the newcomer agents by their original designator names. At the same time, the United States recognized the danger of stockpiling potent unitary agents, and initiated development of a Binary Internally Generated chemical weapon in the EYE series of canister weapons (BigEYE) [8]. In response, development of binary newcomer agents escalated at GosNIIOKhT, and in 1989 the first known binary newcomer agent, Novichok-5 was synthesized off the base structure of A-232 [7].

(a) Organophosphate structural backbone of Novichok agents. R =alkyl, alkoxy, aklylamino, or fluorine; X =halogen (F, Cl, Br) or pseudohalogen (CN). (b) Chemical structure of A-234 as described by Mirzayanov, and (c) by Hoenig and Ellison [18,27].
Novichok class compounds are postulated to be organophosphates containing a dihaloformaldoxime moiety [9]. Several chemical structures purported to be lower potency Novichok agents have been published in the scientific literature with the intention of masking the Novichok program as a pesticide research program [1015]. According to Dr. Mirzavanov, and GosNIIOKhT chemist Vladimir Uglev, hundreds of Novichok agents were synthesized although only Substance-33, A-230, A-232, A-234, Novichok-5, and Novichok-7 are known to be weaponized (Table 1) [6,7,16]. Most weaponized Novichok agents are believed to be binary. In the case of A-234, the binary agents were reported to be acetonitrile and a low potency organophosphate [17]. Novichok agents are also available in liquid form, though they can also be converted into a “dusty” formulation by adsorbing liquid droplets onto a solid carrier like talc, silica gel, fuller’s earth or pumice [18]. Some of these compounds were successfully independently synthesized by the Organization for the Prohibition of Chemical Weapons Central Analytical Database [19].

Table 1

A list of known Novichok agents attributed to the GosNIIOKhT research program and their status.
AgentTypeCurrent status
substance-33UnitaryEstimated 15,000 tons produced. Designated as chemical weapon
A-230UnitaryExperimental quantities produced. Designated chemical weapon (1990)
A-232UnitaryExperimental agent. Not designated, or officially approved
A-234Unitary analog of A-232Unknown
Novichok-5Binary analog of A-232, 8× more effective than VXExperimental agent. Designated chemical weapon (1989)
Novichok-7Binary analog of A-234, 10× more effective than somanExperimental agent. Not designated
Novichok-# (no established designator)Binary analog of Substance-33Adopted as chemical weapon (1990)
Binary Novichok agents possess several military advantages. First, an individual agent, depending on its chemical subgroups, may not violate the Chemical Weapons Treaty and, hence, is “legal.” These subgroups can be innocuous compounds whose sinister intent may be difficult to detect. Second, the components of binary agents are extremely stable and have limited degradation over time. Third, Novichok agents are highly potent, reportedly 5–10 times more so than VX [6,18].
Exposure to Novichok agents is fatal unless aggressively managed. The LD50 of Novichok agents is reportedly approximately 0.22 mcg/kg similar to 2-(dimethylamino)ethyl N,N-dimethylphosphoramidofluoridate (VG), a novel, fourth-generation nerve agent [20]. Like other organophosphate compounds, Novichok agents bind acetylcholinesterase preventing degradation of acetylcholine and producing the cholinergic or muscarinic toxidrome. The Novichok-acetylcholineste
mikenov on Twitter: How does Novichok kill and what does the nerve agent do to the human body? thesun.co.uk/news/6729712/h…
Wed, 15 Apr 2020 11:34:03 -0400
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Coronavirus Questions Answered: What We Know About COVID-19 | Time
Wed, 15 Apr 2020 11:20:38 -0400
Michael_Novakhov shared this story .



Illustration by Jameson Simpson for TIME
April 14, 2020
One of the worst symptoms of any plague is uncertainty—who it will strike, when it will end, why it began. Merely understanding a pandemic does not stop it, but an informed public can help curb its impact and slow its spread. It can also provide a certain ease of mind in a decidedly uneasy time. Here are some of the most frequently asked questions about the COVID-19 pandemic from TIME’s readers, along with the best and most current answers science can provide.
A note about our sourcing: While there are many, many studies underway investigating COVID-19 and SARS-CoV-19, the novel coronavirus that causes the illness, it is still essentially brand new to science. As a result, while we’ve drawn primarily on peer-reviewed studies published in scientific journals, we have cited some yet-to-be-published research into important aspects of COVID-19 when appropriate.

Coronavirus FAQ

What are the symptoms of COVID-19?
Who’s most at risk for COVID-19?
Are children at risk?
How long does COVID-19 last?
How long is COVID-19 infectious in people?
Can I get COVID-19 and the seasonal flu or common cold at the same time?
What’s the treatment for COVID-19?
How does a COVID-19 test work?
Should I get tested?
How does COVID-19 spread?
Is COVID-19 airborne?
Is there any difference between being indoors or outdoors when it comes to transmission?
Do masks work for preventing the spread of COVID-19?
How long does the COVID-19 virus survive on surfaces?
Is there any risk of the COVID-19 virus living on mail & packages?
Is there any risk with food delivery services?
Does rain wash away the COVID-19 virus?
What should I do to shop safely?
Should I worry about my clothes after I’ve been outside?
Can I get COVID-19 more than once?
If I get COVID-19 and recover, am I immune and safe to be around/help out older family and neighbors?
I’ve been social distancing for two weeks. When is it safe for me to go see family?
Can my dog or cat get COVID-19?
Can the COVID-19 virus live on my pet’s fur?
Do flies, mosquitoes, or other insects carry or transmit the virus?
Can cleaning products kill the COVID-19 virus?
Does it matter what type of soap I use to wash my hands?
What are the practices for doing laundry in a shared/public laundry room?



What are the symptoms of COVID-19?


Studies have shown that while some COVID-19 patients get only very mild symptoms or none at all, some can develop severe pneumonia and other health issues. A World Health Organization report from February found that around 80% of patients with laboratory confirmed cases “have mild disease and recover.” Researchers are not certain how many people infected with the virus are nearly or entirely asymptomatic. “There is not a single reliable study to determine the number of [asymptomatic sufferers],” says a metastudy conducted by scientists from Oxford University, and published online on April 6. “It is likely we will only learn the true extent once population-based antibody testing is undertaken,” write the study authors. (The metastudy, which looked at 21 earlier studies from around the world, has not been peer-reviewed.) The only way to know for sure if you are infected with SARS-CoV-19, the virus that causes COVID-19, is to get tested.
FAQ: What are the Symptoms of COVID-19?
A World Health Organization report from February found that around 80% of patients with laboratory confirmed cases “have mild disease and recover.”
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      What Does COVID-19 Do to Your Body? Here's What the Experts Say
      According to a study of nearly 56,000 laboratory confirmed cases cited in the WHO report, the most common symptom, experienced by 88% of confirmed patients, is a fever. The other most common symptoms according to that study are, in descending order:

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      • Dry cough (68%)
      • Fatigue (38%)
      • Coughing up sputum/mucus production (33%)
      • Shortness of breath (19%)
      • Joint or muscle pain (15%)
      • Sore throat (14%)
      • Headache (14%)
      • Chills (11%)
      • Nausea or vomiting (5%)
      • Nasal congestion (5%)
      • Diarrhea (3%)
      • Coughing up blood (1%)
      • Eye discharge (1%)
      One thing missing from this list is anosmia, or loss of sense of smell. Anecdotal reports suggest that people with milder cases of the disease could have telltale symptoms like the loss of their sense of smell and/or taste, however the WHO has not yet added those symptoms to its official list, as the data are not yet strong enough. But an analysis of a COVID-19 symptom-tracking app in the U.K. shows 59% of the 579 users who had tested positive for the disease reported a loss of smell and taste, compared to 18% who did not have the disease.—Billy Perrigo
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      Who’s most at risk for COVID-19?

      At this point, it seems people of all ag
      mikenov on Twitter: All Your Coronavirus Questions, Answered ti.me/3a3GFG5?utm_so…
      Wed, 15 Apr 2020 11:19:26 -0400
      All Your Coronavirus Questions, Answered ti.me/3a3GFG5?utm_so…



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      Coronavirus symptoms: 10 key indicators and what to do |
      Wed, 15 Apr 2020 11:13:27 -0400
      Michael_Novakhov shared this story from www.wfsb.com - RSS Results of type article.

      (CNN) -- Scientists are learning more each day about the mysterious novel coronavirus and the symptoms of Covid-19, the disease it causes.
      Fever, cough and shortness of breath are found in the vast majority of all Covid-19 cases. But there are additional signals of the virus, some that are very much like cold or flu, and some that are more unusual.
      Any or all symptoms can appear anywhere from two to 14 days after exposure to the virus, according to the US Centers for Disease Control and Prevention.
      Here are 10 signs that you or a loved one may have Covid-19 -- and what to do to protect yourself and your family.

      1. Shortness of breath

      Shortness of breath is not usually an early symptom of Covid-19, but it is the most serious. It can occur on its own, without a cough. If your chest becomes tight or you begin to feel as if you cannot breathe deeply enough to fill your lungs with air, that's a sign to act quickly, experts say.
      "If there's any shortness of breath immediately call your health care provider, a local urgent care or the emergency department," said American Medical Association president Dr. Patrice Harris.
      "If the shortness of breath is severe enough, you should call 911," Harris added.
      The CDC lists other emergency warning signs for Covid-19 as a "persistent pain or pressure in the chest," and "bluish lips or face," which can indicate a lack of oxygen.
      Get medical attention immediately, the CDC says.

      2. Fever

      Fever is a key sign of Covid-19. Because some people can have a core body temperature lower or higher than the typical 98.6 degrees Fahrenheit (37 degrees Celsius), experts say not to fixate on a number.
      CNN anchor Chris Cuomo, who is battling the virus from his home in New York, is one of those people.
      "I run a little cool. My normal temperature is 97.6, not 98.6. So, even when I'm at 99 that would not be a big deal for most people. But, for me, I'm already warm," Cuomo told CNN Chief Medical Correspondent Dr. Sanjay Gupta in a CNN Town Hall.
      Most children and adults, however, will not be considered feverish until their temperature reaches 100 degrees Fahrenheit (37.7 degrees Celsius).
      "There are many misconceptions about fever," said Dr. John Williams, chief of the division of pediatric infectious diseases at the University of Pittsburgh Medical Center Children's Hospital of Pittsburgh.
      "We all actually go up and down quite a bit during the day as much as half of a degree or a degree," Williams said, adding that for most people "99.0 degrees or 99.5 degrees Fahrenheit is not a fever."
      Don't rely on a temperature taken in the morning, said infectious disease expert Dr. William Schaffner, a professor of preventative medicine and infectious disease at Vanderbilt University School of Medicine in Nashville. Instead, take your temperature in the late afternoon and early evening.
      "Our temperature is not the same during the day. If you take it at eight o'clock in the morning, it may be normal," Schaffner explained.
      "One of the most common presentations of fever is that your temperature goes up in the late afternoon and early evening. It's a common way that viruses produce fever."

      3. Dry Cough

      Coughing is another common symptom, but it's not just any cough.
      "It's not a tickle in your throat. You're not just clearing your throat. It's not just irritated," Schaffner explained.
      The cough is bothersome, a dry cough that you feel deep in your chest.
      "It's coming from your breastbone or sternum, and you can tell that your bronchial tubes are inflamed or irritated," Schaffner added.
      report put out by the World Health Organization in February found over 33% of 55,924 people with laboratory confirmed cases of Covid-19 had coughed up sputum, a thick mucus sometimes called phlegm, from their lungs.

      4. Chills and body aches

      "The beast comes out at night," said Cuomo, referencing the chills, body aches and high fever that visited him on April 1.
      'It was like somebody was beating me like a pinata. And I was shivering so much that ... I chipped my tooth. They call them the rigors," he said from his basement, where he is quarantined from the rest of his family.
      "I was hallucinating. My dad was talking to me. I was seeing people from college, people I haven't seen in forever, it was freaky," Cuomo said.
      Not everyone will have such a severe reaction, experts say. Some may have no chills or body aches at all. Others may experience milder flu-like chills, fatigue and achy joints and muscles, which can make it difficult to know if it's flu or coronavirus that's to blame.
      One possible sign that you might have Covid-19 is if your symptoms don't improve after a week or so but actually worsen.

      5. Sudden confusion

      Speaking of worsening signs, the CDC says a sudden confusion or an inability to wake up and be alert may be a serious sign that emergency care may be needed. If you or a loved one has those symptoms, especially with other critical signs like bluish lips, trouble breathing or chest pain, the CDC says to seek help immediately.

      6. Digestive issues

      At first science didn't think diarrhea or other typical gastric issues that often come with the flu applied to the noval coronavirus, also known as SARS-CoV-2. As more research on survivors becomes available, that opinion has changed.
      "In a study out of China where they looked at some of the earliest patients, some 200 patients, they found that digestive or stomach GI (gastrointestinal) symptoms were actually there in about half the patients," Gupta said on CNN's New Day news program.
      Overall, "I think we're getting a little bit more insight into the types of symptoms that patients might have," Gupta said.
      The study described a unique subset of milder cases in which the initial symptoms were digestive issues such as diarrhea, often without fever. Those patients experienced delays in testing and diagnosis than patients with respiratory issues, and they took longer to clear the virus from their systems.

      7. Pink eye

      Research from China, South Korea and other parts of the world indicate that about 1% to 3% of people with Covid-19 also had conjunctivitis, commonly known as pink eye.
      Conjunctivitis, a highly contagious condition when caused by a virus, is an inflammation of the thin, transparent layer of tissue, called conjunctiva, that covers the white part of the eye and the inside of the eyelid.
      But SARS-CoV-2 is just one of many viruses that can cause conjunctivitis, so it came as no real surprise to scientists that this newly discovered virus would do the same.
      Still, a pink or red eye could be one more sign that you should call your doctor if you also have other telltale symptoms of Covid-19, such as fever, cough or shortness of breath.

      8. Loss of smell and taste

      In mild to moderate cases of coronavirus, a loss of smell and taste is emerging as one of the most unusual early signs of Covid-19.
      "What's called anosmia, which basically means loss of smell, seems to be a symptom that a number of patients developed," CNN Chief Medical Correspondent Dr. Sanjay Gupta told CNN anchor Alisyn Camerota on New Day.
      "It may be linked to loss of taste, linked to loss of appetite, we're not sure -- but it's clearly something to look out for," Gupta said. "Sometimes these early symptoms aren't the classic ones."
      "Anosmia, in particular, has been seen in patients ultimately testing positive for the coronavirus with no other symptoms," according to the American Academy of Otolaryngology-Head and Neck Surgery.
      A recent analysis of milder cases in South Korea found the major presenting symptom in 30% of patients was a loss of smell. In Germany, more than two in three confirmed cases had anosmia.
      It has long been known in medical literature that a sudden loss of smell may be associated with respiratory infections caused by other types of coronaviruses, so it wasn't a surprise that the novel coronavirus would have this effect, according to ENT UK (PDF), a professional organization representing ear, nose and throat surgeons in the United Kingdom.
      Is there anything you can do at home to test to see if you're suffering a loss of smell? The answer is yes, by using the "jellybean test" to tell if odors flow from the back of your mouth up through your nasal pharynx and into your nasal cavity. if you can pick out distinct flavors such as oranges and lemons, your sense of smell is functioning fine.

      9. Fatigue

      For some people, extreme fatigue can be an early sign of the novel coronavirus. The WHO report found nearly 40% of the nearly 6,000 people with laboratory confirmed cases experienced fatigue.
      Just a few days into his quarantine, Cuomo was already exhausted by the fevers and body aches the disease brings.
      "I'm so lethargic that I can stare outside, and, like, an hour-and-a-half goes by," Cuomo told Gupta on Anderson Cooper 360. "I think I took a 10-minute nap, and it was three and a half hours."
      Fatigue may continue long after the virus is gone. Anecdotal reports from people who have recovered from Covid-19 say exhaustion and lack of energy continue well past the standard recovery period of a few weeks.

      10. Headache, sore throat, congestion

      The WHO report also found nearly 14% of the almost 6,000 cases of Covid-19 in China had symptoms of headache and sore throat, while almost 5% had nasal congestion.
      Certainly not the most common signs of the disease, but obviously similar to colds and flu. In fact, many symptoms of Covid-19 can resemble the flu, including headaches and the previously mentioned digestive issues, body aches and fatigue. Still other symptoms can resemble a cold or allergies, such as a sore throat and congestion.
      Most likely, experts say, you simply have a cold or the flu -- after all, they can cause fever and cough too.

      So what should you do?

      "At this moment, the current guidance -- and this may change -- is that if you have symptoms that are similar to the cold and the flu and these are mild symptoms to moderate symptoms, stay at home and try to manage them" with rest, hydration and the use of fever-reducing medications, said the AMA's Harris.
      That advice does not apply if you are over age 60, since immune systems weaken as we age or if you are pregnant. Anyone with concerns about coronavirus should call their healthcare provider, according to the CDC.
      It's unclear whether pregnant women have a greater chance of getting severely ill from coronavirus, but the CDC has said that women experience changes in their bodies during pregnancy that may increase their risk of some infections.
      In general, Covid-19 infections are riskier if you have underlying health conditions such as diabetes, chronic lung disease or asthma, heart failure or heart disease, sickle cell anemia, cancer (or are undergoing chemotherapy), kidney disease with dialysis, a body mass index (BMI) over 40 (extremely obese) or an autoimmune disorder.
      "Older patients and individuals who have underlying medical conditions or are immunocompromised should contact their physician early in the course of even mild illness," the CDC advises.
      To be clear, you are at higher risk -- even if you are young -- if you have underlying health issues.
      "People under 60 with underlying illnesses, with diabetes, heart disease, immunocompromised or have any kind of lung disease previously, those people are more vulnerable despite their younger age," Schaffner said.
      A history of travel to an area where the novel coronavirus is widespread (and those parts of the world, including the US, are going up each day) is obviously another key factor in deciding if your symptoms may be Covid-19 or not.

      How to be evaluated

      If you have no symptoms, please don't ask for testing or add to backlog of calls at testing centers, clinics, hospitals and the like, experts say.
      "We do not test people with no symptoms because it's a resource issue," Schaffner said about the assessment center at Vanderbilt. "However, we are emphasizing that people who have this small cluster of important symptoms -- fever and anything related to the lower respiratory tract such as cough and difficulty breathing -- reach out to be evaluated."
      If you do have those three signs, where should you go?
      "If you have insurance and you're looking for a provider or someone to call or connect with, there's always a number on the back of your insurance card; or if you go online, there is information for patients," Harris said.
      "If you don't have insurance, you can start with the state health department or the local community health centers, those are officially known as federally qualified health centers," Harris advised, adding that some states have a 1-800 hotline number to call.
      "If there is a testing and assessment center near you, you can go there directly," Schaffer said. "It's always good to notify them that you're coming. Otherwise, you need to call your healthcare provider and they will direct you what to do."
      CNN's Jacqueline Howard contributed to this report.
      mikenov on Twitter: Spotlight on America: Doctors raising red flags about new coronavirus symptoms wjla.com/news/spotlight…
      Wed, 15 Apr 2020 11:12:41 -0400
      Spotlight on America: Doctors raising red flags about new coronavirus symptoms wjla.com/news/spotlight…



      mikenov on Twitter
      Dermatological symptoms may be the latest new coronavirus symptom
      Wed, 15 Apr 2020 11:08:53 -0400
      Michael_Novakhov shared this story .

      The novel coronavirus may cause dermatological symptoms such as pseudo-frostbite, hives and persistent, sometimes painful redness, as symptoms that affect the body outside the respiratory system continue to be found that may be associated with coronavirus infections, according to the French National Union of Dermatologists-Venereologists (SNDV – skin and sexually transmitted disease doctors).
      The organization received numerous reports of cases with these symptoms in COVID-19 patients. They may also appear without respiratory symptoms, according to a press release by SNDV.
      A WhatsApp group of over 400 dermatologists has been organized by SNDV to discuss cases with these symptoms.
      Last week, France's Director General of Health Jerome Salomon was asked whether dermatological issues such as hives could be new symptoms of the 
      coronavirus
      , and responded, "not to my knowledge," according to 
      Le Figaro
      . He added, however, that not everything is known about the virus, "but on this dermatological aspect I have not seen any publication."
      Multiple new symptoms have been discovered over the past month that may be associated with the novel coronavirus, some appearing even without any respiratory symptoms.
      In late March, the British Rhinological Society and the American Academy of Otolaryngology (head and neck surgery and treatment) both reported anecdotal evidence indicating that a 
      loss of smell and taste
       could be a symptom of COVID-19, the disease caused by the virus.
      Reports from multiple countries have indicated that significant numbers of coronavirus patients experienced anosmia, the loss of sense of smell, and ageusia, an accompanying diminished sense of taste, according to The New York Times.
      Medical professionals are unsure what is causing the loss of the senses of smell and taste. Some viruses destroy the cells or cell receptors in the nose, while others infect the brain via the olfactory sensory nerves. The ability to infect the brain may explain some of the cases of respiratory failure in COVID-19 patients; evidence shows that coronaviruses may invade the central nervous system.
      Some COVID-19 patients are also experiencing neurological issues, including confusion, stroke and seizures, according to the Times. Some patients also reported acroparesthesia, a tingling or numbness in the extremities. Others have been afflicted by symptoms of a serious heart attack, but without any blocked arteries.
      Studies on many of the newly realized symptoms have not been done, as physicians handling the coronavirus outbreak are overwhelmed, according to Forbes.
      mikenov on Twitter: Dermatological symptoms may be the latest new coronavirus symptom jpost.com/International/…
      Wed, 15 Apr 2020 11:08:29 -0400
      Dermatological symptoms may be the latest new coronavirus symptom jpost.com/International/…



      mikenov on Twitter
      mikenov on Twitter: What We Know About The Silent Spreaders Of COVID-19 npr.org/sections/goats…
      Wed, 15 Apr 2020 11:06:43 -0400
      What We Know About The Silent Spreaders Of COVID-19 npr.org/sections/goats…



      mikenov on Twitter
      mikenov on Twitter: Did I Have the Coronavirus? nytimes.com/2020/04/13/opi…
      Wed, 15 Apr 2020 10:58:09 -0400
      Did I Have the Coronavirus? nytimes.com/2020/04/13/opi…



      mikenov on Twitter
      Coronavirus destroys lungs. But doctors are finding its damage in kidneys, hearts and elsewhere.
      Wed, 15 Apr 2020 10:52:35 -0400
      The virus also is having a clear impact on the gastrointestinal tract, causing diarrhea, vomiting and other symptoms. One study found that half of ...
      In Italy 109 priests have died of coronavirus
      Wed, 15 Apr 2020 10:52:03 -0400
      In Italy, ”especially in deeply infected areas like Bergamo, [priests and religious] are risking, and sometimes giving, their lives to attend to the spiritual ...
      Coronavirus deaths: Why NI's statistics are changing
      Wed, 15 Apr 2020 10:51:31 -0400
      The release of official figures on coronavirus-related deaths in Northern Ireland is set to change later this week, amid concerns about how care home ...
      Americans push forward as impact of coronavirus felt in every corner of the country
      Wed, 15 Apr 2020 10:51:15 -0400
      WASHINGTON (SBG) - The coronavirus outbreak has left many in ... original stories of endurance from around the country give Americans hope that there ... to examine the racial disparities of COVID-19 cases and deaths nationwide.
      Italy Faces Yet Another Moment of Truth
      Wed, 15 Apr 2020 10:50:40 -0400
      Prime Minister Giuseppe Conte could scupper next week's EU coronavirus talks unless he gets his way on coronabonds. But he has no real leverage.
      Editorial: Coronavirus statistics must be clarified
      Wed, 15 Apr 2020 10:50:24 -0400
      The discrepancy is partially due to the lag between the time statistics were compiled for the state's 24-hour daily coronavirus update and news of ...
      Israel's upward coronavirus trend slowing
      Wed, 15 Apr 2020 10:49:53 -0400
      The upward trend of newly confirmed coronavirus cases throughout the State of Israel is seemingly maintaining a gradual decline. Following the ...
      Germany's corona aid was fast – but so were the fraudsters
      Wed, 15 Apr 2020 10:49:02 -0400
      ... to 225,000 small businesses in a day as part of its coronavirus recovery plan. ... Criminals had built more than 90 fake websites, phishing the data of ... "Our investigation indicates that this was a professionally set up criminal ...
      New Javits Center Video Uncovers Temporary Coronavirus Hospital Construction
      Wed, 15 Apr 2020 10:48:47 -0400
      “With support from a host of federal, state and city agencies, the Javits Center has been transformed into what some are calling the largest hospital in ...
      Here's the evidence: Virus did NOT jump from Wuhan's seafood market
      Wed, 15 Apr 2020 10:48:01 -0400
      ... supports the claim that SARS-CoV-2 (virus that causes COVID-19) came from the Wuhan market. ... Q: Are chimeric visues used as a bioweapon?
      White supremacy, Christian nationalism and the coronavirus: This pandemic has brought out the ...
      Wed, 15 Apr 2020 10:47:31 -0400
      Reportedly, some white supremacists have strategized online about how to use the coronavirus as a biological weapon to infect and kill nonwhites, ...
      Here's the latest info operation to blame the US for coronavirus
      Wed, 15 Apr 2020 10:47:00 -0400
      “It reacted to the virus by accusing the United States of creating it and then hindering Iran's fight against the virus with its sanctions, and by praising the ...
      Iran Calls China's Coronavirus Numbers Are A 'Bitter Prank'
      Wed, 15 Apr 2020 10:45:58 -0400
      Iran's political class has increasingly criticized the administration of President Hassan Rouhani for its handling of the novel coronavirus pandemic, which ...
      US near approving antibody test for COVID-19: Pence
      Wed, 15 Apr 2020 10:45:28 -0400
      Earlier in the week, the FDA also granted emergency use authorization of the first saliva-based coronavirus test. The announcement was made on ...
      What policing during the pandemic can tell us about crime rates and arrests
      Wed, 15 Apr 2020 10:44:41 -0400
      ... prudent given how officer numbers have been depleted due to the coronavirus outbreak. In early April, almost 20% of NYPD officers were out sick.
      mikenov on Twitter: Tweets And News - From Michael Novakhov: » Mayor de Blasio touts $25 million in emergency f... tweetsandnews.blogspot.com/2020/04/mayor-…
      Wed, 15 Apr 2020 10:39:25 -0400
      Tweets And News - From Michael Novakhov: » Mayor de Blasio touts $25 million in emergency f... tweetsandnews.blogspot.com/2020/04/mayor-…



      mikenov on Twitter
      More than 8,200 coronavirus cases on Staten Island; fatality number continues to rise
      Wed, 15 Apr 2020 09:53:51 -0400
      Michael_Novakhov shared this story .

      STATEN ISLAND – The number of coronavirus (COVID-19) cases on Staten Island has surpassed 8,200, while the confirmed death total continued its ascent to 346, data from the city Health Department shows.
      Besides the confirmed fatalities, the Health Department listed an additional 50 deaths in the borough as “probable” due to the coronavirus.
      A death is classified as “probable” if the decedent was a city resident who had no known positive laboratory test for the coronavirus, but the death certificate lists “COVID-19” or an equivalent as a cause of death.
      As of 4:30 p.m. Monday, there were 8,236 confirmed coronavirus cases on Staten Island, according to the Health Department’s most recently published data.
      The agency had been posting updates twice daily – in the morning and late afternoon – but is now only doing so in the afternoon.
      The latest totals are reflective of the prior afternoon’s figures.
      The new case and death tallies represented increases of 38 and 16, respectively, from earlier totals of 8,198 and 330.
      *** CLICK HERE FOR COMPLETE COVERAGE OF CORONAVIRUS IN NEW YORK ***
      Meanwhile, Staten Island’s hospitals continue to report daily patient updates.
      As of Tuesday morning, the number of patients receiving coronavirus treatment on the Island stood at 461, a decline of 23 from Monday morning’s tally of 484, according to information from the borough’s two hospital systems.
      Daily hospitalization numbers had ranged between 507 and 484 from Thursday morning through Monday morning.
      That number had hit 554 last Wednesday.
      It wasn’t immediately clear whether the decrease in patient totals was due, in part, to transfers from the hospitals to other medical facilities around the city.
      At Staten Island University Hospital (SIUH), 300 patients were receiving treatment Tuesday morning – 238 in the Ocean Breeze campus and 62 in the Prince’s Bay facility, said Jillian O’Hara, a spokeswoman.
      That figure represented a decrease of 24 patients from Monday’s total of 324.
      Richmond University Medical Center had 161 coronavirus patients as of Tuesday morning, an increase of one from Monday morning’s tally of 160, Alex Lutz, a spokesman, said. Of those patients, 44 are in the Intensive Care Unit, down from 58 on Monday.
      Across the five boroughs, there were 107,263 coronavirus cases as of 4:30 p.m. Monday, an increase of 450 from that morning’s tally of 106,813 at 9:30 a.m.
      Unfortunately, confirmed coronavirus deaths spiked by 407 over that seven-hour period to a total of 6,589.
      Besides the confirmed total fatalities, the Health Department reported an additional 1,927 deaths as “probable” for the coronavirus.
      Of the 5,167 fatalities thus far investigated in the city, the vast majority probed – 5,034, or 97.4% – occurred in patients with underlying medical issues, said the agency.
      Underlying conditions include diabetes, lung disease, cancer, immunodeficiency, heart disease, hypertension, asthma, kidney disease and gastro-intestinal/liver disease, said the Health Department.
      On the plus side, the number of patients treated for the coronavirus and released from borough hospitals continues to rise.
      That total hit 911 as of Tuesday morning, an increase of 42 from Monday.
      There were 31 new discharges at SIUH, raising the total there to 726, O’Hara said.
      At Richmond University Medical Center, 185 patients had been treated and released as of Tuesday morning, boosting the prior day’s tally of 174 by 11, said Lutz.
      Testing, which officials stress does not necessarily reflect the full spread of the virus, shows 1,730 of every 100,000 Staten Islanders have tested positive, according to 2018 Census data projections and the Health Department’s Monday afternoon data.
      Staten Island retains the highest rate among the five boroughs and accounts for 8% of the city’s total coronavirus cases.
      The Bronx’s infection rate of 1,636 residents per 100,000 is the second highest in the city. Its 23,426 cases account for 22% of the city’s total.
      Queens continues to have the third highest rate of confirmed coronavirus cases in the city, with 1,475 residents per 100,000 testing positive. That borough has 33,616 cases, the most among the five boroughs and comprising 31% of the city’s total.
      Brooklyn, the most populated borough, has the fourth-highest rate of infection per 100,000 residents – 1,091.
      Brooklyn’s 28,183 cases are the second highest among the five boroughs.
      Brooklyn accounts for 26% of the city’s reported coronavirus cases, Health Department statistics show
      Manhattan retains the lowest infection rate among the boroughs with 844 per 100,000 residents testing positive.
      There have been 13,740 positive cases in Manhattan, comprising 13% of the five-borough tally, according to the city’s Health Department.
      mikenov on Twitter: New Johns Hopkins map breaks down COVID-19 data by county, shows demographic information wmar2news.com/news/coronavir…
      Wed, 15 Apr 2020 09:49:22 -0400
      New Johns Hopkins map breaks down COVID-19 data by county, shows demographic information wmar2news.com/news/coronavir…



      mikenov on Twitter
      mikenov on Twitter: COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features | Radiology pubs.rsna.org/doi/10.1148/ra…
      Wed, 15 Apr 2020 09:27:13 -0400
      COVID-19–associated Acute Hemorrhagic Necrotizing Encephalopathy: CT and MRI Features | Radiology pubs.rsna.org/doi/10.1148/ra…



      mikenov on Twitter
      What explains the non-respiratory symptoms seen in some COVID-19 patients? Wed, 15 Apr 2020 08:34: Saved and Shared Stories
      Wed, 15 Apr 2020 09:05:15 -0400
      Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov.

      20200410lnp1-body.jpg


      Saved and Shared Stories 
      What explains the non-respiratory symptoms seen in some COVID-19 patients?
      New York City hospitals cancel temporary workers as coronavirus cases stabilize
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      mikenov on Twitter: New saliva-based coronavirus test unveiled with 'simplified' process finance.yahoo.com/news/coronavir… via @YahooFinance
      Intelligence officials weigh possibility coronavirus escaped from a Chinese lab
      mikenov on Twitter: Intelligence officials weigh possibility coronavirus escaped from a Chinese lab news.yahoo.com/intelligence-o…
      Fauci once dismissed concerns about 'silent carriers' of coronavirus. Not anymore.
      mikenov on Twitter: RT @YahooNews: Dr. Anthony Fauci once dismissed concerns about 'silent carriers' of coronavirus, but not anymore. Here's what changed.
      mikenov on Twitter: RT @MiddleEastMnt: Saudi Arabia carried out 800 executions under King Salman middleeastmonitor.com/20200415-saudi… pic.twitter.com/FuQ3Xsw5Ps
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      mikenov on Twitter: RT @CNNPolitics: Fact check: President Trump denies saying another thing he said and makes more false claims at coronavirus briefing https:…
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      mikenov on Twitter: RT @washingtonpost: Live updates: As U.S. death toll soars, Trump accuses WHO of coronavirus cover-up and suspends funding https://t.co/KTQ…
      mikenov on Twitter: RT @AmbJohnBolton: Withholding US funding from @WHO is the correct response to its coronavirus failures and Chinese influence. It should b…
      Officials Told ‘Bodies Being Piled Up In Nursing Homes’ As Desperate Families Face Silence – CBS New York
      mikenov on Twitter: Coronavirus Deaths: Officials Told 'Bodies Being Piled Up In Nursing Homes' As Desperate Families Face Silence cbsloc.al/2XzVrlq#.Xpbte…
      mikenov on Twitter: RT @washingtonpost: Islamic State cell plotted attacks on U.S. bases in Germany, prosecutors say wapo.st/3betNyg
      mikenov on Twitter: #MayorDeBlasio #GovernorCuomo #NYC #NY #FIRE #STUPID #BRAINLESS #HHC #BUREAUCRATS FOR #INABILITY TO #ORGANIZE #PROPER #CARE & #SAFEGUARDS FOR #STAFF! IT IS THEIR #FAULT! #FIRETHEM #NOW! Up to 20% of #Coronavirus cases are the #he
      mikenov on Twitter: Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM coronavirusalerts.org/?p=75
      mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro
      mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #STUPID! #BRAINLESS! #HHC: #Staff #sickouts #skyrocket at #NYC #hospitals amid #coronavirusoutbreak Wednes
      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM
      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak
      mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro
      Putin Acknowledges That Russia's Coronavirus Outbreak Is Worsening
      Mixed picture in Europe, coronavirus vaccine at least 12 months off: WHO
      Food insecurity concerns escalate during COVID-19 pandemic
      COVID-19 fatality rates vary widely, leaving questions for scientists
      Is corona a biological weapon
      mikenov on Twitter: Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false', via @nzherald nzherald.co.nz/nz/news/articl…
      Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false'
      Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously ...
      mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #Putin #UN #OperationCoronaVirus #Update: "#HealthCareWorkers are 10%-20% of #USCoronavirusCases" tweetsa
      mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #Putin #UN #CoronavirusPandemicInvestigations #CoronavirusGermany #OperationCoronaVirus #Update: "#HealthCa
      7:57 PM 4/14/2020 - Operation CoronaVirus Update: "Health care workers are 10%-20% of US coronavirus cases"
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/quTyP7SxoBaGsM…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/spjm63uykpATWu…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/2BiB3dqiwPXUzb…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/jnCd87icTgTLJn…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/Hb4bxJDvMWp8Ts…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/tfg1Akn6kNFiRc…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search images.app.goo.gl/c1fRPq5zW4K98y…
      mikenov on Twitter: #News - #Coronavirus in #healthcare workers - Google Search google.com/search?q=Coron…
      Health care workers are 10%-20% of US coronavirus cases
      Senate committee to probe China, WHO over coronavirus outbreak
      mikenov on Twitter: Coronavirus in health care workers - Google Search google.com/search?q=Coron…
      Immunity from COVID-19 antibodies not certain, HIV co-discoverer cautions
      New York City Reports 50 Educa
      mikenov on Twitter: Let them mind their own FUCKING bidniz and put up the money themselves, if they want to. twitter.com/thehill/status…
      Wed, 15 Apr 2020 08:41:06 -0400
      Let them mind their own FUCKING bidniz and put up the money themselves, if they want to. twitter.com/thehill/status…
      JUST IN: China, EU push Trump to restore funding to the World Health Organization hill.cm/gBnE8hJ



      249 likes, 107 retweets



      mikenov on Twitter
      mikenov on Twitter: RT @NBCNews: Passwords and email addresses for thousands of Zoom accounts are for sale on the dark web. nbcnews.to/2REfICq
      Wed, 15 Apr 2020 08:38:36 -0400
      Passwords and email addresses for thousands of Zoom accounts are for sale on the dark web. nbcnews.to/2REfICq

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:38pm


      97 likes, 108 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @mod_russia: Экипажи фронтовых бомбардировщиков Су-24М авиаполка Южного военного округа, дислоцированного в Волгоградской области, прист…
      Wed, 15 Apr 2020 08:38:19 -0400
      Экипажи фронтовых бомбардировщиков Су-24М авиаполка Южного военного округа, дислоцированного в Волгоградской области, приступили к подготовке воздушной части военного парада, посвященного 75-летию Победы в Великой Отечественной войне.
      #ВКС #ВВС #Авиация #ЮВО #ПарадПобеды #Cу24 pic.twitter.com/N3X3HLI0Fd

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:38pm


      62 likes, 25 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @BreitbartNews: Wow. trib.al/D6yWwpz
      Wed, 15 Apr 2020 08:37:39 -0400

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:37pm


      320 likes, 185 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @tribelaw: Grim but sadly true
      Wed, 15 Apr 2020 08:37:25 -0400
      Grim but sadly true
      mikenov on Twitter: RT @nytimes: “Never in my life have I had to ask a patient to get off the telephone because it was time to put in a breathing tube.” Doctor…
      Wed, 15 Apr 2020 08:37:14 -0400
      “Never in my life have I had to ask a patient to get off the telephone because it was time to put in a breathing tube.” Doctors treating coronavirus patients have had to re-engineer, on the fly, their practice of medicine and their personal lives. nyti.ms/2XB4oLb

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:37pm


      329 likes, 118 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @thehill: Ocasio-Cortez says it's "legitimate to talk about" sexual assault allegation against Biden hill.cm/A2lTMf3 https://t.c…
      Wed, 15 Apr 2020 08:36:53 -0400
      Ocasio-Cortez says it's "legitimate to talk about" sexual assault allegation against Biden hill.cm/A2lTMf3 pic.twitter.com/Tav4zSgZ4F



      Retweeted by mikenov on Wednesday, April 15th, 2020 12:36pm


      93 likes, 35 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @USNavy: Social distancing doesn't mean you are alone! #ReachOutWednesday Pick up the phone or grab a computer and call a Shipmate, fam…
      Wed, 15 Apr 2020 08:35:16 -0400
      Social distancing doesn't mean you are alone! #ReachOutWednesday
      Pick up the phone or grab a computer and call a Shipmate, family or friend today. Just one call makes someone's day in these trying times. #InThisTogether pic.twitter.com/7jqpfEl6Ot

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:35pm


      863 likes, 267 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @tribelaw: Apart from inexcusably slowing the checks, this display of ego is a reminder to all of us that the one and only thing Donald…
      Wed, 15 Apr 2020 08:35:02 -0400
      Apart from inexcusably slowing the checks, this display of ego is a reminder to all of us that the one and only thing Donald J. Trump cares about is . . . Donald J. Trump.
      washingtonpost.com/politics/comin…

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:35pm


      2588 likes, 829 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @Pontifex: They are called children of God who have learned the art of peace and exercise it, knowing that there is no reconciliation wi…
      Wed, 15 Apr 2020 08:34:30 -0400
      They are called children of God who have learned the art of peace and exercise it, knowing that there is no reconciliation without the gift of one’s own life, and that peace must be sought always and in every situation. #Beatitudes #GeneralAudience

      Retweeted by mikenov on Wednesday, April 15th, 2020 12:34pm


      5547 likes, 991 retweets


      mikenov on Twitter
      mikenov on Twitter: COVID-19 affects more than the lungs cen.acs.org/content/cen/ar… via @cenmag
      Wed, 15 Apr 2020 08:34:15 -0400
      COVID-19 affects more than the lungs cen.acs.org/content/cen/ar… via @cenmag



      mikenov on Twitter
      What explains the non-respiratory symptoms seen in some COVID-19 patients?
      Wed, 15 Apr 2020 08:34:05 -0400
      Michael_Novakhov shared this story .

      20200410lnp1-body.jpgCredit: C&EN/Shutterstock
      While COVID-19 is predominantly a lung (4) infection, symptoms have been reported throughout the body, including the central nervous system (1), eyes (2), nose and mouth (3), heart (5), liver (6), and gut (7).
      While COVID-19, the disease caused by the novel coronavirus SARS-CoV-2, is generally a respiratory infection with coughing and shortness of breath as key features of the illness, some people have reported other symptoms, including loss of smell, heart trouble, and diarrhea.
      These less common symptoms, especially cardiac ones, have caused hospitals to adapt their intake protocols to spot possible COVID-19 patients, says Salim Virani, a cardiologist at Baylor College of Medicine. “Almost all hospitals that I’ve talked to, everybody has a protocol whereby they are testing these patients for COVID-19 as well,” Virani says about people who arrive at the emergency department with heart concerns.
      Scientists say that these non-lung symptoms might also be good indicators of SARS-CoV-2. Once inside a person’s body, the novel coronavirus attaches to a protein on human cells called angiotensin-converting enzyme 2 (ACE2). This enzyme, which is normally involved in blood pressure regulation, sits on the surface of different types of cells, including those in the brain, blood vessels, heart, intestines, and kidneys.
      It’s plausible that the novel coronavirus causes these other symptoms by directly infecting some of these cells. But this infection also can cause a massive immune response, leading to the overproduction of small immune molecules called cytokines. This cytokine storm triggers inflammation and organ damage. It’s been observed in the lungs of the sickest COVID-19 patients, but it likely happens in other organs as well.
      “If you have a severe infection, and there is a systemic response related to that, inflammation can be protective early on,” Virani says. “But then that response itself, when it’s a systemic inflammation all over the body, can become detrimental.”
      Here is a look at some of the body parts where the novel coronavirus might cause other symptoms in people, and what scientists think is behind these symptoms. Because researchers are still learning about SARS-CoV-2, a lot of what they hypothesize is based on previous characterizations of the virus’s cousins, the virus that caused the severe acute respiratory syndrome (SARS) outbreak from 2002 to 2004, and the coronavirus that causes Middle East respiratory syndrome (MERS).
      Some COVID-19 patients have shown up at the hospital confused, or with what doctors call an altered mental status. For example, a flight attendant in her fifties from Detroit developed something called acute hemorrhagic necrotizing encephalopathy. This brain condition is characterized by inflammation and tissue damage and is often linked to viral infections. Brent Griffith, a neuroradiologist at Henry Ford Hospital, led the team of health care workers who described the woman’s condition, which they attribute to cytokine storm and a breakdown of the blood-brain barrier. Using magnetic resonance imaging, they showed damage to her brain, and noted that while they were unable to test for the presence of SARS-CoV-2 in fluid from her central nervous system, the presence of virus isn’t always necessary for acute hemorrhagic necrotizing encephalopathy (Radiol. 2020, DOI: 10.1148/radiol.2020201187).
      Another research team, led by Yan-Chao Li of Jilin University, thinks that based on what we know about where in the body the virus behind the SARS outbreak attacks, SARS-CoV-2 might be able to infect the central nervous system. Li and the team also propose that when the coronavirus infects the brain, it may damage the nerves that regulate breathing, and that this might be one of the reasons why some people end up in respiratory failure (J. Med. Virol. 2020, DOI: 10.1002/jmv.25728).
      There have been some reports of eye inflammation, or conjunctivitis, associated with COVID-19, but these symptoms have been rare. Still, some researchers have wondered whether the virus could get into the body through the eyes. In small studies in China, researchers have detected the virus’s RNA in people’s tears (JAMA Ophthalmol. 2020, DOI: 10.1001/jamaophthalmol.2020.1291).
      Eye cells do express the ACE2 receptor, but these scientists still think eye-related infection or tear-related spread of the virus would be quite rare. Led by Chuan-bin Sun of the Zhejiang University School of Medicine, this team suggests that tears would wash away the virus, and that immune mechanisms in the eyes, led by antibodies and a molecule called lactoferrin, would prevent widespread infection (J. Med. Virol. 2020, DOI: 10.1002/jmv.25859). The American Academy of Ophthalmology has also weighed in on the issue, saying that, “infectious virus has not yet been cultured from the conjunctiva of any COVID-19 patient.”
      Danielle Reed of the Monell Chemical Senses Center says that viral infections often affect our sense of smell, and thus taste, because the infection blocks airways, preventing odorants from interacting with smell receptors. However, in the case of COVID-19, she says, researchers haven’t ruled out direct infection of smell-sensing cells, or some other mechanism affecting the nerves that conduct smell signals to the brain.
      So, Monell, as part of the Global Consortium for Chemosensory Researchers, is gathering data from people who have tested positive for COVID-19, and who are experiencing loss of smell and taste.
      While olfactory neurons do not express ACE2, cells that surround those neurons, and provide structural support, do. The virus could infect and kill these sustentacular cells, weakening the scaffolding that holds olfactory neurons up, and perhaps affecting the neurons’ function. “We envision that they’re taking up the virus,” Reed says. “But, how it’s causing problems with people’s ability to smell is not understood.”
      There is precedence for these sensory symptoms, Reed points out. People with SARS also reported a loss of smell.
      Some people with COVID-19 have had heart attacks, but Baylor’s Virani says that early reports of patients in Seattle and New York indicate that arrhythmia, an irregular heart beat, is the most common cardiovascular symptom. Doctors have also observed inflammation of heart tissue, or myocarditis.
      Heart muscle cells express ACE2, Virani says, and it is possible that SARS-CoV-2 is infecting the heart, but he can’t rule out cytokine storm and what’s happening in the lungs as the culprits behind these cardiac symptoms. “The severity of the heart muscle involvement, in most cases, but not in every case, is actually directly related to the severity of the lung involvement,” he says, adding that in some patients, as their lung disease progresses, markers for cardiac damage also increase. Doctors are treating some of the people with these cardiac symptoms with drugs that block some of the perpetrators of cytokine storm, including interleukin-6.
      In one study of 99 people infected with SARS-CoV-2 in Wuhan, 43 had elevated levels of the liver enzymes alanine aminotransferase, aspartate aminotransferase, and lactic dehydrogenase (Lancet 2020, DOI: 10.1016/S0140-6736(20)30211-7). High levels of these enzymes are a sign of liver damage. In another study of nearly 1,100 people who tested positive for the novel coronavirus, between 28% and 40% had elevated liver enzymes, and the more critically ill they were, the more likely they were to have higher levels (N. Eng. J. Med. 2020, DOI: 10.1056/NEJMoa2002032 .
      Jie Li, who is an infectious disease scientist at Shandong University, and Jian-Gao Fan of the Shanghai Jiao Tong University School of Medicine, wrote in a recent paper that there aren’t many cells in the liver that express ACE2, so it’s not clear if the virus is causing the damage directly itself (J. Clin. Transl. Hepatol. 2020, DOI: 10.14218/JCTH.2020.00019). They point out that cytokine storm might affect the liver, as could sepsis, which is a large scale bacterial infection that seems to trail coronavirus infection in some people.
      Some people who have had SARS or MERS also experienced liver damage, but it’s still too early to say what’s happening with SARS-CoV-2 and the liver.
      As the COVID-2 outbreak spread through Hubei province in China, a team of researchers, led by Lei Tu of Huazhong University of Science and Technology, surveyed about 200 people with COVID-19 to see if they experienced gastrointestinal symptoms and found that 19% reported some combination of diarrhea, vomiting, or abdominal pain. That data makes gastrointestinal distress perhaps the most common non-respiratory symptom of SARS-CoV-2 infection. Their analysis also indicated that some patients went to the hospital complaining about these gastrointestinal issues and no respiratory symptoms, suggesting that some people with COVID-19 could have been missed by doctors. In fact, six of the people they studied never had any respiratory symptoms.
      Tu and colleagues found viral RNA in about half of the stool samples they tested in their study. The team speculates that the inflammatory response to infection could explain intestinal symptoms, as the lungs and gut are linked via the body’s mucosal system in what researchers call the gut-lung axis. But scientists also think it’s possible that the novel coronavirus infects intestinal cells carrying the ACE2 receptor. One study of human tissue from COVID-19 patients found evidence of novel coronavirus proteins inside gastrointestinal cells that express ACE2, suggesting that the virus can infect the human gut. That team concluded that these data suggest gastrointestinal symptoms should not be overlooked in the absence of respiratory illness (J. Gastro. 2020, DOI: 10.1053/j.gastro.2020.02.055).
      Chemical & Engineering News
      ISSN 0009-2347
      Copyright © 2020 American Chemical Society

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      New York City hospitals cancel temporary workers as coronavirus cases stabilize
      Wed, 15 Apr 2020 08:31:32 -0400
      Michael_Novakhov shared this story from Yahoo News - Latest News & Headlines.

      'Accelerate the Endgame': Obama's Role in Wrapping Up the Primary

      Over the past year, Joe Biden and former President Barack Obama practiced a political distancing of sorts, with Obama maintaining a posture of public neutrality in the Democratic primaries, offering counsel to any candidate who called (most did), and Biden saying he wanted to win on his own.But with calibrated stealth, Obama has been considerably more engaged in the campaign's denouement than has been previously revealed, even before he endorsed Biden on Tuesday.For months, Obama had kept in close contact with senior party officials, in hopes of preventing a repeat of the protracted and nasty 2016 primary race.Then, in the weeks after it became clear that Biden was the party's near-certain nominee, Obama -- telling a friend he needed to "accelerate the endgame" -- had at least four long conversations with his former vice president's remaining rival, Sen. Bernie Sanders. Obama's efforts to ease the senator out of the race played a significant role in Sanders' decision to end his bid and endorse Biden, according to people close to the Vermont independent.By that time, Biden and Obama had already begun hashing out the thorny questions of how, when and where to deploy a former president thrust into an unfamiliar role as his sidekick's sidekick.How to proceed is a negotiation between friends but a delicate one. The terms of the reunion, however welcome, are complicated by an intermingling of political and personal issues, according to interviews with a dozen people close to both men who spoke mostly on the condition of anonymity.Biden's team knew better than to ask Obama for his overt support during the primary campaign. But they felt he might have done more to spare them a few tribulations, and were incensed that some former Obama advisers, especially David Axelrod, repeatedly questioned Biden's viability. When Naomi Biden, the candidate's granddaughter, took to Twitter in February to describe the former Obama aide as "a jerk with a microphone," cheering could be heard at the campaign's headquarters in Philadelphia, according to a person who was present. (Axelrod has said he considers himself an impartial observer.)Party officials were more direct, prodding Obama to be more active behind the scenes, especially after Biden had begun his comeback by winning the South Carolina primary. But the former president, often communicating through Eric Schultz, a political aide who has also served as a bridge to the Biden campaign, insisted that his best use would be as a passive peacemaker."He kept his powder dry, and that gave him credibility, which made all the difference," said Tom Perez, the Democratic National Committee chairman, who served as labor secretary under Obama.Now, with the primary campaign over, Biden and his aides are eager to deploy the former president as quickly as possible, especially on fundraising, as they race to compete with President Donald Trump's small-donor juggernaut."Biden has obviously achieved something huge here on his own, but the president is a surrogate unlike anyone else anyone can bring to bear -- I mean, who has Trump got?" said Joel Benenson, Obama's longtime pollster and a top adviser to Hillary Clinton in 2016. "Getting to the point where he can get Obama involved, you know, that's a big deal."Obama is open to whatever the campaign suggests, according to several people familiar with his thinking. But he continues to counsel caution, the better to preserve his political capital and to avoid the perception that he is somehow coming in to rescue Biden.A more immediate matter is the logistical challenge of taking on a sitting president during a pandemic and an economic collapse. And Obama, like Trump, is less adept at recording direct-to-camera pitches than at delivering rousing speeches before live crowds, a scenario that social-distancing restrictions have made impossible for the foreseeable future.The Obama endorsement came in a sober but impassioned 12-minute endorsement video released Tuesday morning. "I'm so proud to endorse Joe Biden for president of the United States," Obama said, his face shot in close-up. "I believe Joe has all the qualities we need in a president right now."Obama offered a preview of how he plans to pitch Biden, less as a traditional stand-alone candidate than as the standard-bearer for a larger Democratic coalition bound by decency and competence. And after drawing Sanders into that fold, calling him "an American original, a man who has devoted his life to giving voice to working people's hopes," he concluded the video with: "Join us. Join Joe."The camps are still working out the details of engaging Obama in fundraising. But David Plouffe, who remains Obama's most trusted political adviser, has offered to pitch in, and plans to participate in several virtual Biden fundraisers that could be a dry run for Obama's participation, according to people briefed on the plans.Biden's emergence as the Democrats' presumptive nominee relatively early in the political calendar is unwelcome news to Trump, his bluster notwithstanding, several of the president's advisers said. Last Thursday, after trying to goad an anti-Biden revolt among Sanders supporters, the president suggested dark motives for Obama's hesitancy in endorsing Biden."You know what? I'll tell you, it does amaze me that President Obama hasn't supported Sleepy Joe," Trump said at a White House coronavirus briefing, in between questions about his administration's response to the crisis. "It just hasn't happened. When is it going to happen? When is it going to happen? Why isn't he? He knows something that you don't know, that I think I know, but you don't know. So it'll be interesting."That claim was Trumpian misdirection. Obama timed his video to follow Sanders' endorsement Monday.But the Biden-Obama relationship, which deepened from a congenial partnership into a real friendship in 2015, when the president consoled Biden during his son Beau's illness and death, is not without complications.Biden is grateful for Obama's friendship but increasingly proud of his historic comeback. When news reports surfaced that Obama had called to congratulate Biden on his victory in South Carolina, the candidate made it clear to his staff that while his connection to Obama played a role in delivering African American voters, Obama "had not lifted a finger" on his behalf, according to a senior Democrat with knowledge of his remarks.Well, maybe a pinkie. Last year, Obama consulted with Biden's team on campaign strategy, and he bucked up Biden after his loss in the Iowa caucuses. In a private dinner last fall with members of the liberal Democracy Alliance, Obama offered thinly veiled criticism of Sanders' "revolutionary" policies and opined that voters wanted change, not to "tear down the system."Obama is relieved that the Democratic contest is over early, but he had other plans for 2020 -- hoping to finish, publish and promote his White House memoirs before the campaign kicked into high gear.He had intended to engage publicly only after the convention (now scheduled for August, at the earliest), in line with his fall barnstorming campaign on behalf of Clinton in 2016 and congressional candidates in 2018. He resisted calls by some Democratic officials earlier this year to intervene on Biden's behalf in the wake of Sanders' victory in the Nevada caucuses, arguing that he did not want to "thumb the scale" for his friend.Nonetheless, he was becoming more agitated by the state of the race as Sanders surged, and Biden slumped. By late February, he was telling people in his orbit that he thought Biden's campaign had an alarming lack of "infrastructure" and shared his doubts about Biden's belief that he could win the nomination after losing Iowa and New Hampshire.Democratic officials say Obama had no direct role in the campaign shake-up that happened soon after. But people with knowledge of the situation say he made it clear that he supported Biden's decision to name a new campaign manager, Jennifer O'Malley Dillon, a former Obama campaign field organizing specialist, and to move another Obama veteran, former White House communications director Anita Dunn, into a more powerful role.Obama did not directly encourage Sanders' rivals to endorse Biden before the decisive Super Tuesday primaries. But he did tell Pete Buttigieg, a moderate, that he would never have more leverage than on the day that he was quitting the race -- and the former South Bend, Indiana, mayor soon joined the avalanche of former candidates backing Biden.Sanders, who in 2016 accused the Democratic establishment of conspiring to support Clinton, took note of all these moves, but he has made no such charges against Obama.In fact, one of his campaign advisers, speaking on the condition of anonymity in the wake of last month's string of Sanders defeats, said the senator was grateful for Obama's neutrality throughout the campaign. And Sanders, who has denied reports that he contemplated a primary challenge to Obama in 2012, had made a point of reaching out to the former president several times in recent months to update him on the progress of his campaign.Before those conversations, the two men had a polite but frosty relationship, and some of their private exchanges over the years devolved into policy debates, former aides said. But Obama saw Sanders' overture as an opening to assume the peacemaker's role he believed himself best suited to play.Since leaving office, Obama has ruminated about what he could have done differently, both as president and as a campaign surrogate for Clinton, to stop Trump's ascent, and concluded that he needed to do more to repair the damage from party infighting."His true north is winning back the White House, period," said Valerie Jarrett, a close friend and adviser to the former president, in a phone interview last month. Obama, she added, would "have backed any nominee, any of them, with the same conviction."Sanders is much closer personally to Biden despite their political differences, but Obama, unlike Biden, remains a trusted figure to many Sanders supporters, so much so that his campaign released an ad that featured a patchwork of clips with Obama lavishing praise on Sanders.In the end, Sanders concluded that negotiating a detente through the former president would ease the blow of his withdrawal on his base. Whether Obama's involvement will ultimately draw Sanders voters to support Biden's candidacy remains an open question, and some supporters, including Sanders' own campaign press secretary, say they won't.In late March, Obama reached out to Sanders. The two men would talk at least three more times, with the former president reassuring Sanders that he had already accomplished much of what he had set out to do, moving the party -- and Biden -- substantially to the left, according to two people with knowledge of their interactions.But, the people said, he mostly listened to Sanders, who was in a reflective mood, speaking candidly about his post-campaign plans and feelings about the race, the kind of conversation the two men had never had before.Sanders, for his part, is intent on protecting his open line of communication with the former president. When asked for a readout during an interview on MSNBC shortly after dropping out last week, he replied, "They're private conversations," waving a don't-even-ask-me-about-it hand at the camera.The interviewer, Chris Hayes, plowed ahead: "Well, can I ask about your conversations with Vice President Biden?""Oh, yes," Sanders answered, with a laugh.This article originally appeared in The New York Times.(C) 2020 The New York Times Company
      mikenov on Twitter: New York City hospitals cancel temporary workers as coronavirus cases stabilize news.yahoo.com/nyc-hospitals-…
      Wed, 15 Apr 2020 08:27:49 -0400
      New York City hospitals cancel temporary workers as coronavirus cases stabilize news.yahoo.com/nyc-hospitals-…



      mikenov on Twitter
      mikenov on Twitter: saliva-based coronavirus test - Google Search google.com/search?q=saliv…
      Wed, 15 Apr 2020 08:22:20 -0400
      saliva-based coronavirus test - Google Search google.com/search?q=saliv…



      mikenov on Twitter
      mikenov on Twitter: New saliva-based coronavirus test unveiled with 'simplified' process finance.yahoo.com/news/coronavir… via @YahooFinance
      Wed, 15 Apr 2020 08:21:13 -0400
      New saliva-based coronavirus test unveiled with 'simplified' process finance.yahoo.com/news/coronavir… via @YahooFinance



      mikenov on Twitter
      Intelligence officials weigh possibility coronavirus escaped from a Chinese lab
      Wed, 15 Apr 2020 08:17:58 -0400
      Michael_Novakhov shared this story from Yahoo News - Latest News & Headlines.

      WASHINGTON — Although the the U.S. intelligence community early on dismissed the notion that the coronavirus is a synthesized bioweapon, it is still weighing the possibility that the pandemic might have been touched off by an accident at a research facility rather than by an infection from a live-animal market, according to nine current and former intelligence and national security officials familiar with ongoing investigations.
      After extensive research, scientists in the U.S. and elsewhere have determined that the new strain of the coronavirus discovered in China in December is, as Chinese officials have maintained, of natural origin, but they are taking seriously that its route to human infection may have started in a lab in Wuhan.
      “It’s definitely a real possibility being bandied about at the high levels of the administration,” said one of the sources, who has knowledge of China and national security.
      “We are actively and vigorously tracking down every piece of information we get on this topic and we are writing frequently to update policymakers,” an intelligence official told Yahoo News. The intelligence community “has not come down on any one theory.”
      While Chinese officials were quick to link the origin of the disease to infected animals at the Wuhan Seafood Market, which was formally closed on Jan. 1, scientists have not traced the initial exposure back to any specific animals. Therefore, an alternative possibility remains — that a natural virus sample being studied at a research laboratory in Wuhan infected a researcher who spread it in the community, or it escaped via hazardous waste or a lab animal.
      There are reasons to be wary of that theory. It may serve as a propaganda tool for politicians who want to fan tensions with China, and many scientists still argue that a natural outbreak is the most likely possibility, dismissing any alternative theory. But finding the source of the outbreak could also be vital in understanding how it spread and how to prevent the next potential pandemic.

      In December, Chinese health officials began to publicly worry that the mysterious cluster of pneumonia patients in Hubei province might be a sign of something ominous. On Dec. 31, the Wuhan Municipal Health Commission formally notified the World Health Organization’s country office in China about the worrying trend.
      Since those initial reports, more than a million people around the world have tested positive for the new, highly infectious strain of coronavirus and its resulting disease, COVID-19. More than 100,000 have died.
      According to multiple news outlets, the intelligence community was gathering information on the outbreak as early as November. By the new year, the White House was being briefed on the potential that the virus would spread globally. Chinese officials were hiding some of the details, intelligence officials said, but they feared things could get much worse. President Trump, however, waited until March to recommend nationwide extreme social distancing measures to slow the outbreak.
      While the severity of the potential pandemic wasn’t understood back in November and early December, sources tell Yahoo News there has been intense internal interest in the source of the outbreak. While the intelligence community is not discounting a range of potential transmission vectors, including contact between humans and animals, officials are seriously pursuing the possibility that a natural sample of the virus escaped a laboratory.
      “It’s absolutely being looked at very closely at the highest levels,” said one intelligence source with knowledge of the investigations. The British government is reportedly considering the same possibility.
      One reason for the suspicion is the lack of information coming from China. Beijing’s quick denials of involvement, and the decision to immediately identify the Wuhan Seafood Market as the source, raised eyebrows among some U.S. intelligence officials.
      “I find it very funny that China very quickly blamed the market,” said one recently retired intelligence official.
      The Chinese government did not respond to multiple requests for comment made through its foreign ministry and its embassy in the U.S.
      In fact, some of the very first cases of COVID-19 were not linked to the market, and there are a number of important research institutions in Wuhan where infectious diseases are studied.
      Those include the Wuhan National Biosafety Lab, the first publicly acknowledged lab with the highest biosafety standards; the Wuhan branch of the Chinese Centers for Disease Control and Prevention; and the Wuhan Institute of Virology, home to one of the world’s top research groups on bat coronaviruses, where scientists have studied thousands of samples.
      The Wuhan Institute of Virology, which collaborates with researchers and institutions around the world, including the U.S. National Institutes of Health, is a key site for the Global Virome Project, a global initiative focused on preventing the next pandemic by researching DNA and RNA of viruses in animals that could potentially infect humans. While that group does not typically work with intact virus samples, according to David Relman, a microbiologist at Stanford University, “it is possible” that the researchers could have collected a virus sample from a bat and been researching it within the lab.
      The new virus’s genome most closely resembles a bat coronavirus discovered in July 2013 in Yunnan province in China, information made public by the Wuhan Institute of Virology only on Jan. 23 of this year. The progenitor of the current virus, says Richard Ebright, a molecular biologist at Rutgers University, could be either the 2013 bat sample or another bat coronavirus that is closely related and hasn’t been discovered or disclosed as of today.
      Not all scientists agree with this possibility. Writing in Nature, a team of five scientists argued that the new virus, SARS-Cov-2, emerged too recently to have been identified, isolated from other virus samples, cultured and then accidentally released from a lab. Because there is so much variety in types of coronavirus in bats and other species, virus specimens are “massively under-sampled,” wrote the authors, making it less likely Chinese researchers discovered this specific strain. “We do not believe that any type of laboratory-based scenario is plausible,” they concluded.
      However, even Chinese researchers initially pointed to the possibility of a lab accident in a study published in February on ResearchGate. “The killer coronavirus probably originated from a laboratory in Wuhan,” wrote researchers — although they also raised the possibility of natural transmission. “Safety level may need to be reinforced in high risk biohazardous laboratories,” continued Botao Xiao and Lei Xiao of Guangxhou’s South China University of Technology. Botao Xiao later withdrew the paper, telling the Wall Street Journal he did not have evidence for his theories.
      Two Chinese universities recently posted online notices placing restrictions on publishing academic research on the origins of the coronavirus, though those have since been removed from the internet.
      Public videos and articles have revealed poor safety standards on the part of some Wuhan researchers, including being exposed to bat urine and failing to wear proper protective equipment. Additionally, there have been incidents of SARS samples escaping from Chinese labs in the past.
      Retired Air Force Brig. Gen. Robert Spalding, a senior fellow at the Hudson Institute and a former National Security Council official who worked on China issues in the Trump administration, told Yahoo News he believes a lab accident is a “definite possibility.”
      “They have had prior accidental releases of the SARS virus. Also it seems the bats were not local to Wuhan. I do not know if the US government is looking into this,” he wrote in an email. But if the Wuhan National Biosafety Lab scientists were dabbling in potentially dangerous research, “Beijing would not want to call attention to [it],” he concluded.
      Zheng-Li Shi, who leads the group studying bat coronavirus samples at the Wuhan Institute of Virology, published a paper in 2016 in the Journal of Virology detailing experiments on two bat coronaviruses with features needed for human infections. According to the paper, the scientists maintained biosafety level two standards while conducting the research, which is in line with the international standards for coronavirus samples except for SARS and MERS.
      There are four different biosafety levels. Level four is reserved for the most dangerous and infectious diseases, such as Ebola. Under biosafety level two, samples are considered “moderate-risk,” according to the CDC, leading to minimal requirements for hand-washing sinks, automatically locking doors and methods to decontaminate waste.
      Those standards may have been inadequate for coronavirus samples, experts argue.
      “Virus collection, culture, isolation, or animal infection at BSL-2,” given the infectiousness of the coronavirus, “would pose a high risk of accidental infection of a lab worker, and from the lab worker, the public,” wrote Ebright in an email to Yahoo News.
      Ebright is one of many scientists who have pushed the global community to improve its handling of dangerous pathogens, a problem not just for China but for labs worldwide. USA Today in 2015 conducted a wide-ranging investigation of accidents, safety violations and potential disasters in U.S. labs, and found problems ranging from infected lab mice escaping to failures with protective gear.
      Relman, who has advised the government on emerging infectious diseases, told Yahoo News that whether the virus escaped from a lab or not — something he personally views as less likely — he hopes the pandemic will spur higher lab safety standards worldwide. “Standards are not clear enough, not uniformly practiced, and are not keeping up with advances in biological technologies — which, in theory, allow many more people to experiment with these viruses,” he wrote.
      The possibility that the pandemic originated in a lab was first discussed publicly in mid-February as China hawks and Trump allies began to push the bioweapon angle. The New York Times reported that the main proponent of the lab accident theory is President Trump’s deputy national security adviser, Matthew Pottinger, a former Wall Street Journal reporter in China with a reputation for hawkish views on Beijing. Pottinger, through an NSC spokesperson, declined to comment.
      Republican Sen. Tom Cotton of Arkansas publicly promoted a range of theories, including that the virus could have been a “deliberate release” or an “engineered bioweapon” that was accidentally leaked. However, Cotton, who sits on the Senate Intelligence Committee, also noted that the culprit could have been “good science, bad safety” or a mistake made in the course of honest research on “diagnostic testing or vaccines.”
      Current and former intelligence officials familiar with internal briefings declined to provide details but noted the lab accident theory being promoted by Cotton may not be so crazy. “Tom Cotton is presenting some useful stuff there,” said one recently retired intelligence official when asked about the theory.
      Another former intelligence official in touch with current officials told Yahoo News that Trump began calling the virus the “Wuhan virus” after intelligence briefings he received on its origin. Critics said this term, which is not used by the scientific community, was bolstering xenophobic attacks on Asian-Americans and Asians worldwide at a time when international cooperation is required to investigate the outbreak.
      The possibility that the virus leaked during a lab accident “is being seriously considered” within the U.S. government, according to another recently retired senior national security official, who pointed to the State Department’s 2019 compliance report on arms control, nonproliferation and disarmament. The report notes that Chinese officials have failed to reassure inspectors they are obeying the Biological Weapons Convention, including by not providing information about research on “numerous toxins with potential dual-use application.”
      The State Department did not respond to requests for comment on whether compliance concerns extend to potential lab accidents of dangerous virus samples. But in late March, Yahoo News reported that the FBI detected samples of the SARS virus and flu in Chinese scientists’ luggage, presenting a “biosecurity risk” for both deliberate acts of terrorism and potential accidents during research.
      According to the Washington Post, U.S. State Department employees visited the Wuhan virology lab in 2018 and sent a cable back home listing safety concerns about the lab’s bat coronavirus studies. Similar concerns were presented about the Wuhan National Biosafety Lab in 2017, though writers at the prestigious scientific journal Nature have since appended a notice arguing that their reporting on past safety concerns should not be used as evidence that a lab accident led to the 2020 pandemic.
      Sources declined to discuss any evidence, if it exists, that points to a potential lab accident, but the intelligence community is not ruling it out.
      “Absent a credible whistleblower or verified primary communication intercept, it will not be possible to prove the origins with certainty,” said Relman, the Stanford microbiologist. “However, with more relevant data, the likelihood of a natural virus versus accidental origin can be strengthened or diminished.”
      One former senior CIA official said that if the virus did originate from a Chinese research institution, the U.S. intelligence community will eventually be able to prove it. “There will be disaffected Chinese sources,” the former official said.
      “Disasters are good for us,” the former CIA official continued. “The crappier the regime, the better it is to recruit sources there.”
      Hunter Walker contributed reporting to this story.
      _____
      Click here for the latest coronavirus news and updates. According to experts, people over 60 and those who are immunocompromised continue to be the most at risk. If you have questions, please refer to the CDC’s and WHO’s resource guides. 
      Read more:
      mikenov on Twitter: Intelligence officials weigh possibility coronavirus escaped from a Chinese lab news.yahoo.com/intelligence-o…
      Wed, 15 Apr 2020 08:17:40 -0400
      Intelligence officials weigh possibility coronavirus escaped from a Chinese lab news.yahoo.com/intelligence-o…



      mikenov on Twitter
      Fauci once dismissed concerns about 'silent carriers' of coronavirus. Not anymore.
      Wed, 15 Apr 2020 08:07:48 -0400
      Michael_Novakhov shared this story from Yahoo News - Latest News & Headlines.

      At Sunday’s White House briefing, Dr. Anthony Fauci, the longtime director of the National Institute of Allergy and Infectious Diseases, suggested that hundreds of thousands — or even millions — of “silent carriers” may be unwittingly spreading the coronavirus across the United States because they don’t realize they’re infected.
      The idea that at least some coronavirus carriers don’t feel sick isn’t new. But the scale of Fauci’s estimate was.
      “It’s somewhere between 25 and 50 percent” of the total, Fauci said. But “right now,” he went on, “we’re just guessing.”
      Fifty percent is a staggering — and scary — number. To put it in perspective, an asymptomatic rate that high would theoretically double the confirmed U.S. case count to more than 700,000 infections (even though the actual number of infections is likely much larger, given all the issues with testing).
      But is Fauci’s new estimate supported by science? And if so, what does it mean for the United States’ efforts to mitigate the spread of the virus and ultimately bring it under control?
      The news might not be as bad as it looks.
      The first thing to note is that Fauci himself expressed a high degree of uncertainty about his own numbers. “I don’t have any scientific data to say that,” he admitted Sunday. “You know when we’ll get the scientific data? When we get those antibody tests out there and we really know what the penetrance is. Then we can answer the questions in a scientifically sound way.”
      Fauci was right to be cautious. As he noted, it’s impossible to say how many carriers never showed symptoms until you’ve tested a bunch of people who never showed symptoms — something that will only happen after the worst of the pandemic is over and scientists start trying to determine, en masse, who does and doesn’t have immunity. (More on that later.)
      But Fauci has reason to suspect the asymptomatic rate could be as high as 50 percent. Researchers initially assumed the coronavirus would spread much like its notorious sibling, the virus that caused SARS — that is, only from people who were clearly sick with fever and cough. “Even if there’s a rare asymptomatic person that might transmit, an epidemic is not driven by asymptomatic carriers,” Fauci himself said on Jan. 28.

      Yet as the deadly pathogen shut down one country after another, evidence began to surface that sick people weren’t the only ones spreading it. Some of the new data came from Wuhan, China, where the pandemic originated. Some of it came from the Diamond Princess cruise ship, where more than 700 captive passengers and crew members tested positive. Some of it came from Iceland, where nearly 5 percent of the total population — sick or not — has been screened for the virus.
      All of it pointed to the same conclusion: Silent carriers are real, and they are most likely infecting others.
      Estimates of the asymptomatic rate have been ticking upward for months. That’s one reason why U.S. authorities recently reversed their earlier guidance and started advising all Americans to wear masks in public.
      For instance, the Chinese Center for Disease Control and Prevention claimed in early February that only about 1.2 percent of the reported cases in mainland China were asymptomatic — “relatively rare,” as a WHO-China joint report put it, and not “a major driver of transmission.”
      Yet in late March, the South China Morning Post reported that more than 43,000 people in China “with no immediate symptoms,” or about a third of the country’s total case count, had tested positive for the virus by the end of February. They had not been included in the government’s official tally.
      “Immediate symptoms” is an important distinction. There is a difference between being asymptomatic (meaning you never get sick) and presymptomatic (meaning you haven’t gotten sick yet). The latter looks like the former, until it doesn’t.
      Yet it’s possible to tell them apart. Once the Diamond Princess docked in Japan on Feb. 3, researchers tested all of the passengers and reviewed those who tested positive for the virus on multiple occasions over a two-week period. They found that 18 percent of the infected passengers remained symptom-free throughout. Researchers then estimated that within the general population — which is younger and healthier overall than the Diamond Princess passengers, and therefore less likely to develop symptoms — that might translate to a 40-percent asymptomatic rate.
      “The substantial asymptomatic proportion for COVID-19 is quite alarming,” one of those epidemiologists, Dr. Gerardo Chowell of Georgia State University, told the New York Times.
      Most recent estimates have been in this range. A report based on a group of two dozen people in China said 29 percent; another based on screenings of 565 Japanese citizens evacuated from Wuhan said 30 percent. Last week Centers for Disease Control and Prevention Director Robert Redfield told NPR that “one of the [pieces of] information that we have pretty much confirmed now is that a significant number of individuals that are infected actually remain asymptomatic. That may be as many as 25 percent.” New CDC data shows that among confirmed cases, the percentage of children who show symptoms is 20 points lower than the percentage of adults who show symptoms — suggesting that minors could be a major source of covert spread.
      The highest rate so far came from a biopharma company called deCODE, which has tested 9,000 nonsymptomatic, nonquarantined residents of Iceland on behalf of the country’s chief epidemiologist. Although fewer than 1 percent of the tests came back positive, the company’s founder told CNN that around 50 percent of those who tested positive said they didn’t feel sick.
      That may be the source of Fauci’s high-end estimate; on Sunday, he didn’t cite any particular studies, and gesturing to the other experts onstage, he noted that “even among us, good friends that we are, we differ.”
      Either way, asymptomatic transmission presents a significant near-term challenge. Several studies have also shown that people infected with the coronavirus are most contagious one to three days before they begin to show symptoms, and researchers in China recently discovered that one asymptomatic carrier had just as much virus in his system as his symptomatic peers — meaning that he was probably just as contagious.
      The result is that Americans who feel perfectly fine must now choose to believe they’re protecting others by wearing masks in public, and authorities in areas where almost no one has tested positive must now decide to get ahead of the curve by issuing shelter-in-place orders that may look at first like overkill. According to the New York Times, a new study by disease modelers at the University of Texas at Austin suggests that “even counties with just a single reported case have more than 50 percent likelihood that a sustained, undetected outbreak — an epidemic — is already taking place.” Once there are five cases in a county, that probability rises to 85 percent.
      In the long term, however, a huge, hidden population of asymptomatic cases may actually prove to be helpful. For one thing, it would mean that the coronavirus isn’t as deadly as initially feared, which could ease anxieties and inform public-health approaches going forward. It would also mean societies and economies could return to normal sooner than anticipated — assuming that universal antibody tests show that hundreds of thousands (or even millions) of people who never felt sick are now immune. The first such U.S. test was approved by the Food and Drug Administration on April 2.
      “Making sure we are testing asymptomatic individuals to understand more about this virus is critical,” California Gov. Gavin Newsom said Monday. “It’s all part of figuring out whether people have immunity … in order to get [them] back into the workforce, or at least back in society.”
      So as frightening as Fauci’s 50-percent estimate sounds today, Americans may ultimately be grateful if his “guess” turns out to be correct.
      _____
      Click here for the latest coronavirus news and updates. According to experts, people over 60 and those who are immunocompromised continue to be the most at risk. If you have questions, please refer to the CDC’s and WHO’s resource guides. 
      Read more:
      mikenov on Twitter: RT @YahooNews: Dr. Anthony Fauci once dismissed concerns about 'silent carriers' of coronavirus, but not anymore. Here's what changed.
      Wed, 15 Apr 2020 07:31:46 -0400
      Dr. Anthony Fauci once dismissed concerns about 'silent carriers' of coronavirus, but not anymore. Here's what changed.

      Retweeted by mikenov on Wednesday, April 15th, 2020 11:31am


      24040 likes, 8018 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @MiddleEastMnt: Saudi Arabia carried out 800 executions under King Salman middleeastmonitor.com/20200415-saudi… pic.twitter.com/FuQ3Xsw5Ps
      Wed, 15 Apr 2020 07:30:50 -0400
      Saudi Arabia carried out 800 executions under King Salman middleeastmonitor.com/20200415-saudi… pic.twitter.com/FuQ3Xsw5Ps



      Retweeted by mikenov on Wednesday, April 15th, 2020 11:30am


      4 likes, 6 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @MilHistNow: RIGHT NOW in 1865, Abraham Lincoln dies from gunshot wounds he sustained nine hours earlier at Ford's Theater. "There lies…
      Wed, 15 Apr 2020 07:30:10 -0400
      RIGHT NOW in 1865, Abraham Lincoln dies from gunshot wounds he sustained nine hours earlier at Ford's Theater. "There lies the most perfect ruler of men the world has ever seen," remarked War Secretary Edwin Stanton. "Now he belongs to the ages." pic.twitter.com/2sCwY1NopT



      Retweeted by mikenov on Wednesday, April 15th, 2020 11:30am


      67 likes, 39 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @CNNPolitics: Fact check: President Trump denies saying another thing he said and makes more false claims at coronavirus briefing https:…
      Wed, 15 Apr 2020 07:29:29 -0400
      Fact check: President Trump denies saying another thing he said and makes more false claims at coronavirus briefing cnn.it/34BABnc pic.twitter.com/fVvUXO8DFV



      Retweeted by mikenov on Wednesday, April 15th, 2020 11:29am


      126 likes, 61 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @tribelaw: As we watch the disgraceful daily display put on by this inept, narcissistic president, I find myself thinking: America must…
      Wed, 15 Apr 2020 07:29:15 -0400
      As we watch the disgraceful daily display put on by this inept, narcissistic president, I find myself thinking: America must rid itself of this awful guy. Every Democratic campaign ad this fall needs to convey this truth: Vote Trump out of office: Your life depends on it.

      Retweeted by mikenov on Wednesday, April 15th, 2020 11:29am


      1873 likes, 513 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @washingtonpost: Live updates: As U.S. death toll soars, Trump accuses WHO of coronavirus cover-up and suspends funding https://t.co/KTQ…
      Wed, 15 Apr 2020 07:28:56 -0400
      Live updates: As U.S. death toll soars, Trump accuses WHO of coronavirus cover-up and suspends funding wapo.st/2Vwj1Nb

      Retweeted by mikenov on Wednesday, April 15th, 2020 11:28am


      75 likes, 38 retweets


      mikenov on Twitter
      mikenov on Twitter: RT @AmbJohnBolton: Withholding US funding from @WHO is the correct response to its coronavirus failures and Chinese influence. It should b…
      Wed, 15 Apr 2020 07:28:39 -0400
      Withholding US funding from @WHO is the correct response to its coronavirus failures and Chinese influence. It should be a warning flare to the entire UN system that the US will not settle for poor performance #COVID19

      Retweeted by mikenov on Wednesday, April 15th, 2020 11:28am


      842 likes, 237 retweets


      mikenov on Twitter
      Officials Told ‘Bodies Being Piled Up In Nursing Homes’ As Desperate Families Face Silence – CBS New York
      Wed, 15 Apr 2020 07:19:41 -0400
      Michael_Novakhov shared this story from CBS New York.


      NEW YORK (CBSNewYork) – Some say family members living in New York nursing homes are like prisoners being held in captivity.
      They can’t reach them, as the number of coronavirus deaths statewide are spiking, and some wonder what the state and city are doing to help, reports CBS2’s Lisa Rozner.
      A truck acts as a temporary morgue outside New Jewish Nursing Home on West 106th Street in Manhattan.
      The lawyer for the King David Rehab Center in Gravesend says it has made similar arrangements for bodies after COVID-19 patients were transferred there last month.
      “The percentage of loss of life is getting higher in nursing homes compared to the hospitals,” said Gov. Andrew Cuomo.

      CORONAVIRUS PANDEMIC

      Statewide there have been nearly 2,500 deaths in nursing home and adult care facilities.
      An employee who doesn’t want to be identified at the Crown Heights Center for Nursing and Rehabilitation gave CBS2 a video from last week showing nurses begging for COVID tests after seeing 22 deaths in seven days.
      MORECoronavirus Update: National Guard Deployed As COVID-19 Hits Over Half Of All NJ Nursing Homes, Causing Death Toll To Spike
      Representatives for The Chateau at Brooklyn Rehabilitation & Nursing Center in Sheepshead Bay dispute allegations that dead patients were being left in their beds.
      Brooklyn Borough President Eric Adams says he has received multiple calls with similar concerns.
      He and Public Advocate Jumaanee Williams are asking the state to mandate homes enable video communication with residents, provide personal protection equipment to staff and allow random inspections.
      The inspections are needed “to see how these patients are being treated,” said Adams.
      “We’ve gotten calls about bodies being piled up in nursing homes,” said Williams. “We don’t have the luxury of time in responding to this. The mayor and the governor have thousand to tens of thousands of folks.”
      CORONAVIRUS: NY Health Dept. | NY Call 1-(888)-364-3065 | NYC Health Dept. | NYC Call 311, Text COVID to 692692 | NJ COVID-19 Info Hub | NJ Call 1-(800)-222-1222 or 211, Text NJCOVID to 898211 | CT Health Dept. | CT Call 211 | Centers for Disease Control and Prevention
      Another “Jane Doe” who wants to remain anonymous says her mom is at a facility in Flatbush.
      “The doctors are not calling, family members don’t know if their loved one or family members are still alive,” she said.
      Stephen Hanse heads the organization that reps nursing homes and long-term care facilities.
      “By law their family and loved ones have to be informed,” he said. “We’re looking for first and foremost assistance to bring in workers.”
      The governor’s office did not directly answer CBS2’s questions about whether that help would be provided.
      mikenov on Twitter: Coronavirus Deaths: Officials Told 'Bodies Being Piled Up In Nursing Homes' As Desperate Families Face Silence cbsloc.al/2XzVrlq#.Xpbte…
      Wed, 15 Apr 2020 07:18:22 -0400
      Coronavirus Deaths: Officials Told 'Bodies Being Piled Up In Nursing Homes' As Desperate Families Face Silence cbsloc.al/2XzVrlq#.Xpbte…



      mikenov on Twitter
      mikenov on Twitter: RT @washingtonpost: Islamic State cell plotted attacks on U.S. bases in Germany, prosecutors say wapo.st/3betNyg
      Wed, 15 Apr 2020 07:07:19 -0400
      Islamic State cell plotted attacks on U.S. bases in Germany, prosecutors say wapo.st/3betNyg

      Retweeted by mikenov on Wednesday, April 15th, 2020 11:07am


      71 likes, 26 retweets


      mikenov on Twitter
      mikenov on Twitter: #MayorDeBlasio #GovernorCuomo #NYC #NY #FIRE #STUPID #BRAINLESS #HHC #BUREAUCRATS FOR #INABILITY TO #ORGANIZE #PROPER #CARE & #SAFEGUARDS FOR #STAFF! IT IS THEIR #FAULT! #FIRETHEM #NOW! Up to 20% of #Coronavirus cases are the #he
      Wed, 15 Apr 2020 07:02:31 -0400
      #MayorDeBlasio #GovernorCuomo #NYC #NY
      #FIRE #STUPID #BRAINLESS #HHC #BUREAUCRATS FOR #INABILITY TO #ORGANIZE #PROPER #CARE & #SAFEGUARDS FOR #STAFF! IT IS THEIR #FAULT! #FIRETHEM #NOW!
      Up to 20% of #Coronavirus cases are the #healthcare #workers.
      Abolish the #INCOMPETENT HHC! pic.twitter.com/MI7eEPzMKJ





      mikenov on Twitter
      mikenov on Twitter: Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM coronavirusalerts.org/?p=75
      Wed, 15 Apr 2020 06:47:21 -0400
      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM coronavirusalerts.org/?p=75



      mikenov on Twitter
      mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro
      Wed, 15 Apr 2020 06:46:36 -0400
      Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro



      mikenov on Twitter
      mikenov on Twitter: #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr #STUPID! #BRAINLESS! #HHC: #Staff #sickouts #skyrocket at #NYC #hospitals amid #coronavirusoutbreak Wednes
      Wed, 15 Apr 2020 06:44:11 -0400
      #CIA #FBI #ODNI #USMilitary #USIntelligenceCommunity
      #US #Senate #House #Trump #CoronavirusPandemic #Elections2020 #NewAbwehr
      #STUPID! #BRAINLESS! #HHC:
      #Staff #sickouts #skyrocket at #NYC #hospitals amid #coronavirusoutbreak Wednesday April 15th, 2020
      tweetsandnews.blogspot.com/2020/04/staff-… pic.twitter.com/lrjGpUVgPK





      mikenov on Twitter
      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak Wednesday April 15th, 2020 at 6:16 AM
      Wed, 15 Apr 2020 06:35:03 -0400
      Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov.

      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak

      1 Share
      April 14, 2020 | 6:02pm
      staff sickouts skyrocket at NYC hospitals amid coronavirus pandemic
      A nurse wears protective gear outside Elmhurst Hospital in Queens. REUTERS/Jeenah Moon
      The number of health care workers calling in sick at the city’s public hospitals has skyrocketed amid the coronavirus pandemic — with the absentee rate doubling compared to before the killer virus slammed the city.
      The situation is so dire that top officials with Health + Hospitals are cracking the whip — demanding a doctor’s note to document illness for a sick day.
      An April 10 memo sent out by top H + H brass to employees at the network of 11 hospitals and clinics suggested that workers at some facilities might be taking advantage of the epidemic because there are “very high rates of call outs and absences that do not appear to be consistent with patterns of CO
      Staff sickouts skyrocket at NYC hospitals amid coronavirus outbreak
      Wed, 15 Apr 2020 06:16:29 -0400
      Michael_Novakhov shared this story from Carl Campanile – New York Post.

      Skip to main content
      April 14, 2020 | 6:02pm
      Enlarge Image
      staff sickouts skyrocket at NYC hospitals amid coronavirus pandemic
      A nurse wears protective gear outside Elmhurst Hospital in Queens. REUTERS/Jeenah Moon
      The number of health care workers calling in sick at the city’s public hospitals has skyrocketed amid the coronavirus pandemic — with the absentee rate doubling compared to before the killer virus slammed the city.
      The situation is so dire that top officials with Health + Hospitals are cracking the whip — demanding a doctor’s note to document illness for a sick day.
      An April 10 memo sent out by top H + H brass to employees at the network of 11 hospitals and clinics suggested that workers at some facilities might be taking advantage of the epidemic because there are “very high rates of call outs and absences that do not appear to be consistent with patterns of COVID infection.”
      “Because all of you are critically needed in our facilities, we have to address this issue so that some of our staff is not bearing an extra burden for those who are staying home without approved leave,” the note sent by Health + Hospital’s chief medical officer, Dr. Machelle Allen, and the head of human resources, Yvette Villanueva said.
      The memo, first obtained by The City, added, “As a response to this staffing emergency, we will be implementing new processes to ensure that those who are out and using sick or COVID leave are entitled to use that leave.”
      Health + Hospitals staff requesting sick leave now must provide a doctor’s note or other proof that they tested positive for COVID-19 test or are displaying symptoms from the virus or another other illness within five days to get sick pay.
      Both H + H CEO Dr. Mitchell Katz and Mayor Bill de Blasio said maintaining adequate staffing has been a major concern because a workforce stretched thin by high sickouts and toiling under hazardous conditions as they try to save very sick coronavirus patients.
      Nurses at many hospitals have complained of a shortage of personal protective equipment such as masks and gowns, exposing them to COVID-19 from patients and others. Some have died from the coronavirus.
      Katz said “a lot of people, large numbers of people are calling in sick — double the usual rate. … We’re definitely seeing a large number of people missing in action.”
      Katz, in an interview with the Journal of the American Medical Association Monday, said that many hospitals workers are sick from COVID exposure but others are out because they’re scared about getting infected and spreading COVID to other family members.
      He said it’s a big morale booster when sick nurses and doctors recover from COVID-19 and return to the front.

      see also

      “It’s a very fluid, difficult situation right now,” said, Katz.
      He repeatedly called the medical workers “heroes” and said he’s even trying to find a way to give them bonuses during tough fiscal times triggered by the pandemic.
      De Blasio, during a Tuesday press briefing, said Health + Hospitals is hiring, adding, “We need those key health care workers right now.”
      Unlike other departments such as the NYPD, Health + Hospitals has not provided specific stats on its absenteeism rate. The mayor promised Tuesday the data will be released soon.
      Asked about the sick out memo, Health + Hospitals issued a statement Tuesday that said, “We are in unprecedented circumstances and our frontline heroes are going above and beyond to keep New Yorkers safe.
      “We are doing everything we can to adjust to a rapidly evolving situation, and in the process reduce undue burden on employees and ensure that our facilities are staffed appropriately. Understandably these are frightening times, and we are all pulling together so that we can save more New Yorkers.”

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      mikenov on Twitter: Staff sickouts skyrocket at NYC's hospitals amid coronavirus outbreak nypost.com/2020/04/14/sta… via @nypmetro
      Wed, 15 Apr 2020 06:16:16 -0400
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      mikenov on Twitter
      Putin Acknowledges That Russia's Coronavirus Outbreak Is Worsening
      Tue, 14 Apr 2020 21:08:30 -0400
      Russian President Vladimir Putin said "everything is under control" early in the coronavirus pandemic. As the number of Russian victims increases, his ...
      Mixed picture in Europe, coronavirus vaccine at least 12 months off: WHO
      Tue, 14 Apr 2020 21:07:52 -0400
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      Food insecurity concerns escalate during COVID-19 pandemic
      Tue, 14 Apr 2020 21:06:04 -0400
      NORTH CENTRAL WEST VIRGINIA (WDTV) -- Thousands out of work and local food sources are closed as the COVID-19 pandemic exacerbates one ...
      COVID-19 fatality rates vary widely, leaving questions for scientists
      Tue, 14 Apr 2020 21:04:47 -0400
      ... scientists who are still learning about the coronavirus that causes the illness. ... We haven't done a very simple test in epidemiology, which is to try to ...
      Is corona a biological weapon
      Tue, 14 Apr 2020 21:04:32 -0400
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      mikenov on Twitter: Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false', via @nzherald nzherald.co.nz/nz/news/articl…
      Tue, 14 Apr 2020 21:01:40 -0400
      Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false', via @nzherald nzherald.co.nz/nz/news/articl…



      mikenov on Twitter
      Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously false'
      Tue, 14 Apr 2020 21:00:29 -0400
      Michael_Novakhov shared this story from New Zealand Herald - Top Stories.

      When a new flu-like virus first emerged out of Wuhan, two "dangerously false" assumptions started to spread about who was affected by COVID-19, one expert claims.
      The editor of a prestigious British medical journal has slammed the "dangerously false" information that initially circulated about coronavirus, warning it is a more serious disease than previously thought.
      The Lancet editor Richard Horton has been an outspoken critic of the UK government's failure to prepare for the COVID-19 pandemic despite warnings in late January about the new disease emerging from Wuhan.
      He has previously referred to this failure, inadequate testing and lack of supplies of personal protective equipment (PPE) as a "national scandal". Now, in an article published in the Lancet he said early comments the disease was flu-like and only affected older people were misconceptions.
      "As deaths accumulate, the early message that severe acute respiratory syndrome coronavirus 2 causes mostly a mild illness has been shown to be dangerously false," he wrote.
      "One in five patients develop complications and are at grave risk. A further misunderstanding concerns age.
      "An impression was given that only older people are at risk of serious illness. But the average age of non-survivors is under 70 years. Two-thirds of those admitted to hospital in China were younger than 60 years."

      In Australia, three people in their thirties were reported to be on ventilators in intensive care wards last week, with Deputy Chief Medical Officer Paul Kelly calling it a "wake up call" for younger people.
      NSW Health statistics show the 20-39 year old age group has the highest number of cases, with slightly more women than men contracting the virus.
      China has been widely criticised for failing to warn the world early enough that the mysterious new disease was being transmitted between humans in Wuhan. That secrecy, combined with world leaders being slow to prepare, has led to an unprecedented pandemic that has infected more than 2 million people and killed more than 119,000 worldwide.
      The virus has also seen billions of people warned to stay home and created an economic crisis not seen since the Great Depression, with countries only now grappling with how to lift restrictions and return to a semblance of normality.
      There are more than 6300 confirmed COVID-19 cases in Australia, with 2870 in New South Wales, 1291 in Victoria, 998 in Queensland, 433 in South Australia, 527 in Western Australia, 150 in Tasmania, 103 in the Australian Capital Territory and 28 in the Northern Territory.
      The death toll now stands at 62, after a sixth person died in Tasmania earlier today.
      Horton said the public health crisis has seen patient numbers in intensive care doubling every two days and doctors left feeling overwhelmed and bewildered.
      "Deaths are so frequent that hospitals have created emergency mortuary space, often in car parks, moving bodies at night to avoid media scrutiny," he wrote.
      "Intensive care teams are doing truly remarkable work. But it is a huge physical and mental struggle."
      "The focus of the political debate about coronavirus disease 2019 (COVID-19) has so far been almost exclusively about the public health dimensions of this pandemic. But at the bedside there is another story, one that has so far been largely hidden — a story of terrible suffering, distress, and utter bewilderment."
      The UK remains in the eye of the storm, with more than 11,329 deaths and intensive care units under pressure. Medical bosses believe cases will peak next week and the country is expected to remain in lockdown for another three weeks.
      UK Prime Minister Boris Johnson has tested negative for the disease after being discharged from intensive care and is now in recovery at his country retreat, Chequers.
      On Tuesday, new figures revealed the number of virus deaths in Britain could be 15 per cent higher than previously believed according to data on deaths outside of hospital.
      The Office for National Statitstics said 6235 people in England and Wales had died by April 3 with mentions of COVID-19 on their death certificates.
      "When looking at data for England, this is 15 per cent higher than the NHS (National Health Service) numbers as they include all mentions of COVID-19 on the death certificate, including suspected COVID-19, as well as deaths in the community," ONS statistician Nick Stripe said.
      div id="nzh-datavis-root__card" class="nzh-datavis">‌
      In London, more than 46 per cent of deaths in week 14 of the year involved COVID-19, according to initial figures.
      The UK government has received major criticism for failing to conduct widespread testing for coronavirus and pursuing a strategy of "herd immunity". Doctors and nurses on the frontline in NHS hospitals have also warned a lack of PPE has put lives at risk.
      Horton previously wrote the NHS has been "wholly unprepared for this pandemic" and it was "impossible to understand why".
      He said chief medical officers had a duty to put the country on high-alert following warnings published in late January, however a lack of action has led to "chaos and panic" in which staff and patients would "die unnecessarily."
      "It is, indeed, as one health worker wrote last week, "a national scandal". The gravity of that scandal has yet to be understood."
      The World Health Organisation (WHO) has warned new cases might be easing in parts of Europe but the outbreak has not peaked yet.
      "The overall world outbreak, 90 per cent of cases are coming from Europe and the United States of America. So we are certainly not seeing the peak yet," WHO spokeswoman Margaret Harris said.
      In Australia, Prime Minister Scott Morrison dismissed claims social restrictions would be easing up soon, but said there should be a "reward" for the nation's "discipline and patience".
      "Yes, we've had a good couple of weeks but that does not a virus beat. That's why we have many more in front of us before we could even possibly contemplate the easing of restrictions," he told Sky News on Tuesday.
      He added: "There has got to be a reward for all of this great effort going in, and there will be, but we've got to make sure it is done at the right time."
      "We don't want to end up like New York or like London or like in Spain or in Italy or any of these places," he said.
      "And the decisions and actions we've taken together as a country and the discipline and patience shown by Australians has meant that we've been able to avoid those horror scenarios which, you know, Australia is not immune to.
      Last updated: Tue 14th April at 8:52 pm
      Covid 19 Coronavirus: Medical journal editor says early reports of flu-like virus were 'dangerously ...
      Tue, 14 Apr 2020 20:57:58 -0400
      When a new flu-like virus first emerged out of Wuhan, two "dangerously false" assumptions ... This is a biological weapon developed by the USA.
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      7:57 PM 4/14/2020 - Operation CoronaVirus Update: "Health care workers are 10%-20% of US coronavirus cases"
      Tue, 14 Apr 2020 20:43:43 -0400
      Michael_Novakhov shared this story from Tweets And News - From Michael Novakhov.



      Health care workers are 10%-20% of US coronavirus cases

      https://tweetsandnews.blogspot.com/2020/04/657-pm-4142020-health-care-workers-are.html
      ______________________________________________________

      Operation CoronaVirus Update: "Health care workers are 10%-20% of US coronavirus cases"


      It looks like the Coronavirus was introduced in the US not in January of 2020, but earlier, possibly much earlier: in the fall of 2019 or prior to that, around the summer of 2019. It is difficult to determine this exactly, of course. 

      Now we started to see the tip of the iceberg. This figure: 10-20% health care workers of all cases, probably indicates, that the virus was circulating for some time, and the un-diagnosed infectious people were infecting the health care workers, who in turn were unknowingly infecting the new cohorts of their patients, who saw them for the other reasons. 

      It also looks like there are at least two, maybe three or more distinct clinical entities of this illness: 1) Acute, with severe cardio-pulmonary symptoms, often lethal, in the otherwise non-compromised patients, in which the coexisting or superimposed Chemical agents', the various types of the "Novichoks" effects, are possible; 2) The subacute,  3) The moderately and mildly symptomatic, and 4) The asymptomatic clinical types. All of them might be the different illnesses with various causes and their combinations. We do not have enough of the clinical experiences and enough of the observations of these phenomena to classify them definitely at this point. 

      I would not rely on the Chinese medical conceptualizations of their clinical observations too much. All these phenomena have to be approached anew, with the open mind and the unbiased vision. 

      Of course, the most concerning are the acute types of the conditions, for which I considered the possible simultaneous use of the Chemical agents or weapons, under the guise of infection or simultaneously, in some forms or fashions. 

      At least some of these cases might be the targeted killings and the Mafia jobs. This whole affair smells strongly of the Mafia and some of the mysterious powerful Intelligence groups involvement. The recent simultaneous losses in the NYPD, of two detectives from Queens, are somewhat puzzling and alarming. 

      I think, with all the humble awareness of our universal and omnipresent human propensity towards ignorance reserved, that the FBI, with all their limitations and possible reluctance, should investigate this whole affair as the criminal matter of the extraordinary proportions. 

      In fact, we might be dealing with the well organized, well thought out and coordinated attempt on the part of the TOC - Transnational Organized Crime to take over the Civilized World and to bend it to their will. The prison releases, which are practiced out of the utter humanitarian necessity, may be the part of their tactics and design. In a way, if it is so, it can be viewed as the assault on the Justice system in the U.S.. 

      I hypothesized earlier, that there is the entity that is above the Mob hierarchically and  organizationally, and I called it the New Abwehr. For the German Military Intelligence, throughout their complex and tortuous history, the close and intimate ties with the Organised Crime were often the matters of survival, time tested traditions, and the sheer necessity.  


      The very peculiar place of Germany in this global Pandemic lends further support to this hypothetical construct and concept: it looks like Germany was very well prepared and she was well aware of what is coming. See my previous posts for more details. 

      As unprecedentedly and shockingly sad as it is, we have to find enough strength and wisdom to investigate this occurrence very, very thoroughly, professionally, and with the highest of qualities. 

      Michael Novakhov

      7:57 PM 4/14/2020
      __________________________________________

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      Tue, 14 Apr 2020 17:45:29 -0400
      Michael_Novakhov shared this story from CoronaVirus News Review In Brief.

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